ID A0A367KV71_RHIST Unreviewed; 655 AA.
AC A0A367KV71;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Autophagy-related protein 27 {ECO:0000256|ARBA:ARBA00013776};
GN ORFNames=CU098_011860 {ECO:0000313|EMBL:RCI05772.1};
OS Rhizopus stolonifer (Rhizopus nigricans).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=4846 {ECO:0000313|EMBL:RCI05772.1, ECO:0000313|Proteomes:UP000253551};
RN [1] {ECO:0000313|EMBL:RCI05772.1, ECO:0000313|Proteomes:UP000253551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSU 92-RS-03 {ECO:0000313|EMBL:RCI05772.1,
RC ECO:0000313|Proteomes:UP000253551};
RX PubMed=29674435; DOI=10.1534/g3.118.200235;
RA Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA Heitman J., Vilgalys R., Stajich J.E.;
RT "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL G3 (Bethesda) 8:2007-2018(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004358}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004358}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the ATG27 family.
CC {ECO:0000256|ARBA:ARBA00005363}.
CC -!- SIMILARITY: Belongs to the CDC50/LEM3 family.
CC {ECO:0000256|ARBA:ARBA00009457}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCI05772.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PJQM01000307; RCI05772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367KV71; -.
DR STRING; 4846.A0A367KV71; -.
DR EnsemblFungi; RCI05772; RCI05772; CU098_011860.
DR Proteomes; UP000253551; Unassembled WGS sequence.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR InterPro; IPR018939; Autophagy-rel_prot_27.
DR InterPro; IPR005045; CDC50/LEM3_fam.
DR InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR InterPro; IPR044865; MRH_dom.
DR PANTHER; PTHR10926; CELL CYCLE CONTROL PROTEIN 50; 1.
DR PANTHER; PTHR10926:SF0; CELL CYCLE CONTROL PROTEIN 50A; 1.
DR Pfam; PF09451; ATG27; 1.
DR Pfam; PF03381; CDC50; 1.
DR SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR PROSITE; PS51914; MRH; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000253551};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 382..555
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 74225 MW; 0066C036B7D39347 CRC64;
MTKKETDENG EQVKKSRRPM DGAFRQQRLP AWQPVLTPRT VLPTLFIVGI LFCPAGGLLW
WNSNKVNPNI SDKNFDVFRM QPPAYAYTNA TSFLDTDWEN PNNLTIPRCT IDFTIPTTMK
APVYMYYRLT NFYQNHRQYI KNFDDTQLLG NRASGSTLRT NCDPLAYDDT GKIIYPCGLI
ANSMFNGNHF VYLRLRNIAW PSDKQKYGRT QYQPSEIVPP PNWAQRYPNG QYTNEYPPPD
LSTQERFMVW MHVAALPDFR KIWGRNDTLD LPAGRYRAYV DMNFDTRQYG GEKWLVLSTT
TGMGGRNPYL GIAYMSVGAL CIFLGLLFTI RHCIKPRKLG DESYLSWNQP GGGLPSNSNK
MMKTTFSLAL ILYSSVALAV QPYCQLGYKP IGDKDLQLDL SKLNKDFVVF QNETTPPTVT
SIMTQINLCD PLNIPDEPEN HDICPKGTLI CRRTIHVKKN VETVNIVQPI ARDMDNKLNA
EFKPVRSEDD ATKSGYQYSV NLNGGEYNGR AQSALVTLEC DESQSRSDEP KSPVIISYNN
NVLTLQWKTV FACATKAGEK VPDDKPSTPP PSQGDNTKEG MSGMGIFFTI LFVLAGVYFV
GGAIYNYKMY NARGLDLIPH RDFWFDLPYL IRDLIAHIID SVMSRRRGAG GYVAV
//
