ID   A0A367KVS8_RHIST        Unreviewed;       783 AA.
AC   A0A367KVS8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE            EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN   ORFNames=CU098_012216 {ECO:0000313|EMBL:RCI06257.1};
OS   Rhizopus stolonifer (Rhizopus nigricans).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX   NCBI_TaxID=4846 {ECO:0000313|EMBL:RCI06257.1, ECO:0000313|Proteomes:UP000253551};
RN   [1] {ECO:0000313|EMBL:RCI06257.1, ECO:0000313|Proteomes:UP000253551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LSU 92-RS-03 {ECO:0000313|EMBL:RCI06257.1,
RC   ECO:0000313|Proteomes:UP000253551};
RX   PubMed=29674435; DOI=10.1534/g3.118.200235;
RA   Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA   Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA   Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA   Heitman J., Vilgalys R., Stajich J.E.;
RT   "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL   G3 (Bethesda) 8:2007-2018(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCI06257.1}.
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DR   EMBL; PJQM01000194; RCI06257.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A367KVS8; -.
DR   STRING; 4846.A0A367KVS8; -.
DR   EnsemblFungi; RCI06257; RCI06257; CU098_012216.
DR   Proteomes; UP000253551; Unassembled WGS sequence.
DR   GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IEA:InterPro.
DR   CDD; cd09138; PLDc_vPLD1_2_yPLD_like_1; 1.
DR   CDD; cd09141; PLDc_vPLD1_2_yPLD_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 3.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   InterPro; IPR016555; PLipase_D_euk.
DR   InterPro; IPR015679; PLipase_D_fam.
DR   PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR   PANTHER; PTHR18896:SF186; PHOSPHOLIPASE D; 1.
DR   Pfam; PF00614; PLDc; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   PIRSF; PIRSF009376; Phospholipase_D_euk; 2.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253551}.
FT   DOMAIN          159..186
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          569..596
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   REGION          534..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..560
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   783 AA;  90678 MW;  CE50B31FA7EE06E9 CRC64;
     MPVLNHIANK IKHKLRDTVS CIVNPESNIE DEEEEEYLAQ GHRYESFAPV RHDAMVKFFI
     DGHDYCWAVS EAIESAKEVI FIEDWWLYLR RPPAKYPEYR IDALLKRKAE EGVMIYIVVY
     KEVELALTLD SAHTKKTLQS LHENIIVQRH PDHAVGGTFF WSHHEKFVVV DNRIAFVGGI
     DLCFGRWDTH AHRLADFHSS DPTYEIFPGQ DYSDARLKDF INVKEWDMRL IDKTIVPRMP
     WHDMALCVLG KAVLDVSRHF CDRWNFIKQQ KSLDKQNAPF LKPPVGGYSS YQNFKIPLES
     RLLRSYHFDH ATHGVKGTSR VQVLRSSAEW SSGIKLEHSI QNAYIDVISN ANHYIYIENQ
     FFITTTEKDN SYIIKNQIGD AIVKRIIKAH EEQEKFKVFV LIPLMPAFPA DLSTKEAATA
     KLVMYYQYVS ICSGPKSILD KLEKAGIDPN EYIKFYSLRS YDRINRPMVE EMMAREAGYT
     PLDHYGRPIL TKKEAEKSEE EDRPLPPAGF VLPQDRPPME GFIAATTIAP DAMGGGNKVM
     EEPWVNDRPD HRPRDEFNER QEASDYVTEE LYIHGKLLIA DDRIVIMGSA NLNDRSQCGD
     RDSEIALMVD DRDMIESRMN NQPYQASRFA ATLRRQLWKE HLGLLKEEEM DFVTPAMLPL
     PVPQVDLTKT KEDFWVMDPL DEDTLVRWNN TAANNTKAFR EVFHCVPDDT ITNWEEYHKF
     YPDPEKINLG HIHDPEMPVQ EIRENLDKIH GHLVEFPTKF LSYEDLQGDS IPIVGGAVQE
     LYT
//