ID A0A367L3B8_9HYPO Unreviewed; 1674 AA.
AC A0A367L3B8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=L249_5116 {ECO:0000313|EMBL:RCI08925.1};
OS Ophiocordyceps polyrhachis-furcata BCC 54312.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=1330021 {ECO:0000313|EMBL:RCI08925.1, ECO:0000313|Proteomes:UP000253664};
RN [1] {ECO:0000313|EMBL:RCI08925.1, ECO:0000313|Proteomes:UP000253664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC 54312 {ECO:0000313|EMBL:RCI08925.1,
RC ECO:0000313|Proteomes:UP000253664};
RX PubMed=26511477; DOI=10.1186/s12864-015-2101-4;
RA Wichadakul D., Kobmoo N., Ingsriswang S., Tangphatsornruang S.,
RA Chantasingh D., Luangsa-ard J.J., Eurwilaichitr L.;
RT "Insights from the genome of Ophiocordyceps polyrhachis-furcata to
RT pathogenicity and host specificity in insect fungi.";
RL BMC Genomics 16:881-881(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCI08925.1}.
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DR EMBL; LKCN02000017; RCI08925.1; -; Genomic_DNA.
DR STRING; 1330021.A0A367L3B8; -.
DR Proteomes; UP000253664; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000253664}.
FT DOMAIN 8..350
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1540..1663
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 609..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1089..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1205..1232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1406..1471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1604..1623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 742..787
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 618..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1412..1426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1450..1467
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 97..104
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1674 AA; 185429 MW; FEC4A15223C86F5D CRC64;
MPPAGGGNIK VVVRIDRGSK CIVSMKDNQT ILTPPDSPAG RAAKETAAKT FAFDRSYWSF
SKDDASYAGQ SNLFGDLGKP LLDNAFQGYN NCIFAYGQTG SGKSYSMMGY GKEVGIIPNI
CQEMFRRIQA IQTLDHSTKC TVEVSYLEIY NERVRDLLNP STKGNLKVRE HPSTGPYVED
LAKLVVGSFQ EIEHLMDEGN KARTVAATNM NETSSRSHAV FTLMLTQRKH DAETNMDMEK
VAKISLVDLA GSERATSTGA TGARLKEGAE INRSLSTLGR VIAALADLST GKKKKNSGQV
PYRDSVLTWL LKDSLGGNSM TAMIAAISPA DINYDETLST LRYADSAKRI KNHAVINEDA
NARMIRELKE ELALLRSKLG GSGAASSPAS GEVYADDTPL EQQMVTITGA DGAVKKVSKA
DIAEQLSQSE KLLTDLNQTW EQKLQKTEEI HKEREAALEE LGISIEKGFV GLHTPKKMPH
LVNLSDDPLL AECLVYNLKP GTTTVGNGQN ADHHHQAYIR LNGSRILHDH CAFENAPDGT
VTVIPRENAP VMVNGKRIEE PIQLHSGYRV ILGDFHIFRF NHPMEARAER AEVVGHSLLR
QSLTASQISA LDRSSPCHSP RLGHDRSFSK SSEPSIDYRP DSPRNGRDSD WSLARREAAG
AILGTDQNLA SLTDEELNAL FEDVQRARAE RVNVRDDGED TESVTSYQLR DKYMSTGTID
NFSLDTALTM PSTPKHTEPE TREEVADEVE EMRREKARME AELQELKADL LKQLDLQREQ
YEEKMDKLDP LKRPRPNPRL SEKEAARARA AVRVWRGRRF VKMAESVLQE AATLKEAQIM
SNELNESVVF QFTVVDIGHV LCSSYDMVLN GLTGEGEDGA LEETAKPCIG IRVMDYRNSV
VRLWSLEKLQ DRLRQMRQMH QYLDQPEYAQ HLSLDNAFAE TCMPSYTLIG EVDVPLAAVF
ESRVHDLGLD VLSPHTSHTV GIVRLSLEPS HARAPSSRLK FNVVMRELLG FAEREGTEVH
AQLFIPGVPE EEGITTTQMI RDFDEGPIRF ESVHNMSVPL SAPRDVTLRV ALFARVSSMH
LDKLASWDDM RDSSGKGLLP SKSSSCASSS SSSSSSSSRL NESQFLTQEK HDLLSRVQML
ELSEEGEYRP VEVTQTSELD TGTFQLHQGL QRRISISLSH SSGDALPWGG VTAVRVGKVR
LVDSAGKTPD MGGEEPDVTL TTGTPPVFRD RSNGTRSVTL TAQWDSSLHN SLLLDRVTAE
RYRVQMTISW EMSSEKLAEP MRFAQKVCVQ VLPRTFVRQQ SMFSGLFQQV RFVRSSTGIF
TLTLRPVPIK RVGDLWRASS RHDYVKGEEK LVRWAPRGVS LVTDFMAARK KRRRMAEIGA
MQTRLLALGF RESGKKTGAE SAAAAIVTRQ DDDNSNHNKG VVDDDDADVL NDTPDTSQAP
SINEEERDEG NEEGRGEEGE EEVEEEEEKT VKVLQADKDG STRLLSKCVA LWTKYPDPLS
RILSPANTAS PRNGIAPDLP PASTAPRLAA TVVRVPKNPT LLRGGYLLVP SDVSSSSQRW
VKRFVELRRP YLHIHSASDG DEVALVSLRN ARVDSQPEVC GLLQGGGADT GEEEEEEEGG
GSNARRFHTA VFAIYGTDNT WLFAARSERD KMDWIFRIDQ TYLTPMNGGS PAGW
//
