ID   A0A367LQ20_9HYPO        Unreviewed;       555 AA.
AC   A0A367LQ20;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE            EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE   AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
DE   Flags: Fragment;
GN   ORFNames=L249_2784 {ECO:0000313|EMBL:RCI16554.1};
OS   Ophiocordyceps polyrhachis-furcata BCC 54312.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=1330021 {ECO:0000313|EMBL:RCI16554.1, ECO:0000313|Proteomes:UP000253664};
RN   [1] {ECO:0000313|EMBL:RCI16554.1, ECO:0000313|Proteomes:UP000253664}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC 54312 {ECO:0000313|EMBL:RCI16554.1,
RC   ECO:0000313|Proteomes:UP000253664};
RX   PubMed=26511477; DOI=10.1186/s12864-015-2101-4;
RA   Wichadakul D., Kobmoo N., Ingsriswang S., Tangphatsornruang S.,
RA   Chantasingh D., Luangsa-ard J.J., Eurwilaichitr L.;
RT   "Insights from the genome of Ophiocordyceps polyrhachis-furcata to
RT   pathogenicity and host specificity in insect fungi.";
RL   BMC Genomics 16:881-881(2015).
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC       pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00005190}.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
CC       {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCI16554.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LKCN02000001; RCI16554.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A367LQ20; -.
DR   UniPathway; UPA00618; UER00672.
DR   Proteomes; UP000253664; Unassembled WGS sequence.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018485; FGGY_C.
DR   InterPro; IPR018484; FGGY_N.
DR   PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR   PANTHER; PTHR10196; SUGAR KINASE; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|RuleBase:RU003733};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253664};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|RuleBase:RU003733}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..555
FT                   /note="glycerol kinase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016835502"
FT   DOMAIN          72..303
FT                   /note="Carbohydrate kinase FGGY N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00370"
FT   DOMAIN          314..503
FT                   /note="Carbohydrate kinase FGGY C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02782"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RCI16554.1"
SQ   SEQUENCE   555 AA;  59565 MW;  18E0F339973BD50F CRC64;
     AHFGFLWLLA AAHDTIVSSS LPLDFSLQGK NDGRQDPGQR RRKRLCWEHR SGHDLDPFSY
     LQSGRRARCW SSSPICSKHP QPGWHEHDPL ELLRSVETCI QHAVSDFRAS GHHTAQIRAI
     GLANQRETLV AWDTATGEPL CDAVVWSDTR TAPLVRELKA RDGADVLVHR CGQPPSTSAS
     AIKLLWLLCH VEAVARAYDA GRLAVGTVDT WLIYRLNGGV RRPGGPIYVT DSTNASRTMW
     MDIRTRQYDH ELLSFFGVDR AKLTLPTIVS SSHPTAFGAL AYGPLAGTRI AACLGDQSAA
     LVGHGGFSPG KAKSTYGTGC FLLYNVGPEP VISKNGLQAT VAYDLGDGRP PAYALEGSVS
     VAGSGINFLV NNLDFVDSHK AIDHLALSVP DNGGVYFVTA FSGLLAPYWI DDAQGTLFGL
     TAHTQKGHIA RATLEAVCHQ TAAILDAMAA DSGHALDSLA VDGGLAGSDV CMQTQADLSG
     IPVDRPCMRE ATSLGAALAA GLATGVWDGL DQLVHVGTSG RSLFRPGIVK EERCARRRRW
     ARAVEMSRGW LAEVA
//