ID A0A367RRP1_9NOSO Unreviewed; 1057 AA.
AC A0A367RRP1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=RND transporter {ECO:0000313|EMBL:RCJ39165.1};
GN ORFNames=A6770_12030 {ECO:0000313|EMBL:RCJ39165.1};
OS Nostoc minutum NIES-26.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=1844469 {ECO:0000313|EMBL:RCJ39165.1, ECO:0000313|Proteomes:UP000252107};
RN [1] {ECO:0000313|Proteomes:UP000252107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tabuchi Yagui T.R.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCJ39165.1}.
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DR EMBL; LXQD01000076; RCJ39165.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367RRP1; -.
DR Proteomes; UP000252107; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF78; CATION OR DRUG EFFLUX SYSTEM PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000252107};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 342..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 871..891
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 898..917
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 929..949
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..988
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1000..1027
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 371..497
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1038..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1057 AA; 115164 MW; 8B51E22698FA915B CRC64;
MFVDFFIRRP VFTSVCAILI LLVGAISIPT LPTAQYPDIS PTQITVSANY VGASAEVVEN
TVTTVLERQI NGVEGLKYMT SSSSNNGNST ITVTFDAARN KDIAAVDVQN RVSVAEPQLP
EAVQRTGVTV NKQSNNILLA MGLYSDNQKF DNVFLSNYAD LYIIDGLKRI NGVSEAQIFG
ERRYAMRLWL DPNRLASRSL TAQDVIDALN EQNLQVGAGQ IGQQPSQPDQ MYQIDLQAVS
RLTEPSEFAD IVIKTGADGT LIKLKDIGRA ELGAQDYNSF LRFRGNEGVG IGIFATPGSN
ALDVAKAVKA EMAQLAQRFP PGMEYQVAFD TTSFVEASLA EVVKTLIEAI ALVVLVIYIF
LQDWRTTLIP VIVVPLTLVG TFAFIKVFGF SINTLTMFGL TLATGLVVDD AIIVVENISR
LIEDEGMPPR QAASESMREL FGAVIATSLV LMAVFVPVAF FPGATGQIYK QFALTIAFSM
AISTFLAITL TPSLSALLLR RGQRPRGWLG WIFDRINRFI DWIRRGYERI LNRLTRMTAI
VVLLFILSLG VTGWLYISVP TAFIPDDDQG YFITIIQGPE GVSLNYTSKV MAQVEKEILK
LPEVTGTFAI GGFGFSGNSA NSGAIFTTLK PWEERHESGQ SAAAIIGKLG GVLSAIPEAR
IFPVNPPSIQ GLGSFGGFQF QLQDRAGNSG LNTMLQVMGQ LLQRGNQTPG LQAVFSTFSA
NTPQMLIEVD RNKAKALQVD VDEIFNTLQS YLGSRYVNDF NLLQRTYRVY VQADAQFRSN
PDDIERLYVR SVNNQMIPLS NLVKITPNTG AQTINHFNLF RSIEINGSAA PGYSSGQATS
AMEKLAQEVL PATMGYEWAG VTAEEKESGG LAPLIFGLGL VFVFLVLAAQ YENYVDPLII
MLSVPLAILG ALSAQSLRGL PNDVFCQVGL VMLIGLASKN AILIVEFANQ LREQGLSITK
AAVQASQERL RPILMTSLSF IFGIWPLVNP EGAGAASRKS LGTAVAGGMI VSTLLSLFVV
PILYIVIGRI RDRLRSRRKP QLTDSSHDEK VPSASHR
//
