ID A0A367XPK1_9ASCO Unreviewed; 572 AA.
AC A0A367XPK1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20 {ECO:0000313|EMBL:RCK54702.1};
GN Name=THI20_1 {ECO:0000313|EMBL:RCK54702.1};
GN ORFNames=Cantr_03767 {ECO:0000313|EMBL:RCK54702.1};
OS Candida viswanathii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=5486 {ECO:0000313|EMBL:RCK54702.1, ECO:0000313|Proteomes:UP000253472};
RN [1] {ECO:0000313|EMBL:RCK54702.1, ECO:0000313|Proteomes:UP000253472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20962 {ECO:0000313|EMBL:RCK54702.1,
RC ECO:0000313|Proteomes:UP000253472};
RA Ahn J.;
RT "Whole genome sequencing of Candida tropicalis (genome annotated by CSBL at
RT Korea University).";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCK54702.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QLNQ01000030; RCK54702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367XPK1; -.
DR STRING; 5486.A0A367XPK1; -.
DR Proteomes; UP000253472; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RCK54702.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253472};
KW Transferase {ECO:0000313|EMBL:RCK54702.1}.
FT DOMAIN 30..311
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 348..570
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 572 AA; 63148 MW; DBF455A064901609 CRC64;
MKTTVLALRR ADNATPKPSL DAVMTVAGSD SSGGAGIEAD LKTFSAFGVF GMTCITALTA
QNTTGVKTFD KTSRSLMHEI LTANLDDMLF GYDTKEEAPL KAIKTGMLTE EAIRELVAFL
PRINEYDVKL VIDPVMVSTS GSKLSDDEGM ALCVKSLIPG AALLTPNFPE AEALFKLTSG
ADKEVDIKSL EDFVEFVIAL QKSLKCKNLL VKGGHIPFTQ GDVPAKDLKE KNLKIKDVLY
ESEEDKVTIF ESDYIDSTDN HGSGCTLASA IAANIAKGLP LDESIAVSVD FIHRGMTSLK
KKLGAGNGPL NHNVAPVHNV SSIMKGLNEM PKLIVNGNDT FLDYLTNHPR VRDNWKAYTQ
HPFVKALAEN KLPFENFVYY LKQDYHYLVN YAQVQSFAGA VAPTYQQTHA QATIIGEIVT
EIEKHKQRLS KHYNIDYERD MDFDVQLGPG PACIAYCNYL IEASKTEDFL GIKTAVSPCL
HGYAAAGMYG QKIRKNSTDL GVVTEEQSKV YQSWLDEYSS EWYIGADLEG RKALQLLIQD
VDVNDKRIEE LVDIFNDVTK LEIGFWDECL NL
//
