ID A0A367Y5S0_9ASCO Unreviewed; 825 AA.
AC A0A367Y5S0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Cullin-4B {ECO:0000313|EMBL:RCK60351.1};
GN Name=Cul4b_1 {ECO:0000313|EMBL:RCK60351.1};
GN ORFNames=Cantr_08183 {ECO:0000313|EMBL:RCK60351.1};
OS Candida viswanathii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=5486 {ECO:0000313|EMBL:RCK60351.1, ECO:0000313|Proteomes:UP000253472};
RN [1] {ECO:0000313|EMBL:RCK60351.1, ECO:0000313|Proteomes:UP000253472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20962 {ECO:0000313|EMBL:RCK60351.1,
RC ECO:0000313|Proteomes:UP000253472};
RA Ahn J.;
RT "Whole genome sequencing of Candida tropicalis (genome annotated by CSBL at
RT Korea University).";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCK60351.1}.
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DR EMBL; QLNQ01000026; RCK60351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367Y5S0; -.
DR STRING; 5486.A0A367Y5S0; -.
DR Proteomes; UP000253472; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000253472}.
FT DOMAIN 466..693
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 26..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 825 AA; 96003 MW; AD891267C085A0EB CRC64;
MSNTKNNSVS SMLDLNNASL NTLSTATSAN SATPVPPERS VSHLTSTTPS PRLYHRTTED
SLEPQDSKRK KLNTPLTAAT QSVDAMEEIE KLNALALSTV DAILLDLPLD HSVGFLAHQF
LKLCKSKHLL QNFLMHQIHS KIDNDLVANI KPQIEDALGG TVNALAFTEK FFDVFDSWYA
RMVKLSKVFV YLDTNYLAVH TTRPQLLPFA ISLFKDHVIL GTTELSRGLI EQYYLLLRTW
RRDVMLDVNA SEPDQHLYEM AIKFTKLLYE SRSTRFEFVD NLIELTVNYY SGLRLTWMRE
NKEPFSYIQQ VFKAMNENLK FFSVAIKNDY FLKKLFSKLR WNLIFIKFND VLQNVFEFLV
DHPKELLLIY RYCELAEDDY GLNGMATLSH QWGKFTKRRF DEIITSNEEA KTGWLVINEL
VKSFKYFETL TEKQLLNNNI EFKLRYALTQ AVNGSASRKS FIISQLAKYC DAYFRQKLNV
PYKEFAENFL IILKSIGDLL EFVDVYKRDL SKRMLFSSRF NREDESDLAG RLREHLGPTD
ESHSLTVIFA DFEKKYASLA MVPRREEILA DSFKFEPLIL TKKEWPDIPN NEDMSSFKLN
LVLQRMLESM TTQYQKISSK HKLRQLDWTN YKLHQVTIST TFKQGEKEIT GNLLQIQVIM
LFGEDNDGYT IDQLAALTGL NRSFLIKVLN SITTEKYKIL VVKDGKYHFN EGFTDKSKSI
KLPMIRESAP RADQQQQQQQ QEEEQRQLEN AIQTNRDDEF KSCVVKIMKQ EQRLDIYELL
NKCIAVLEKK QPVDFAKLKV IIEKLIETEY LERDDADKNI LIYIP
//
