ID A0A368FRY0_ANCCA Unreviewed; 966 AA.
AC A0A368FRY0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=ANCCAN_19174 {ECO:0000313|EMBL:RCN34971.1};
OS Ancylostoma caninum (Dog hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN34971.1, ECO:0000313|Proteomes:UP000252519};
RN [1] {ECO:0000313|EMBL:RCN34971.1, ECO:0000313|Proteomes:UP000252519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Baltimore {ECO:0000313|EMBL:RCN34971.1,
RC ECO:0000313|Proteomes:UP000252519};
RA Mitreva M.;
RT "Draft genome of the hookworm Ancylostoma caninum.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCN34971.1}.
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DR EMBL; JOJR01000717; RCN34971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368FRY0; -.
DR STRING; 29170.A0A368FRY0; -.
DR Proteomes; UP000252519; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18501; BACK_ANKFY1_Rank5; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 7.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR049763; ANKFY1_BACK.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00248; ANK; 18.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 168..200
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 212..244
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 280..312
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 313..345
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 722..754
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 841..873
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 910..961
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
SQ SEQUENCE 966 AA; 104886 MW; B85A909412F0B7AD CRC64;
MTRSNHWNDL EGLDSVEIKD TSFEAFEVVY RWMYMDVLPR SKFSNELLKE VCQIAFRYHF
TGLQARCVQL LKARVDVSNC ISLYDFADVE NVIDLRDYCG AVVAAHWNEF KPQQFAHLPA
PSLFRLLKKN SHHVLHSIIQ LNREDVLLLY FIENDSKVSA LVNAIDQTGL SPLELALTSG
HINMANQLLS KNANCNAVDE AGKSILARMI EKGRTAILLS IVSGNLPLAK VLINNHADVV
KADGEGRSPL SVALFERNDL DLSAQIVKLG GISVVNHRID KESLLHIAVK RDSLEISKFL
LENNAVVDVE DKSGITPLEV AVRQNNAGMV NLLLSHGASV RVPRNGQSYI LHTAVSKGAQ
MLKVFAEKAK DVDWSASGVL SYALDEKALD CARIVVSAGA QVDSKDSEGN SLLVQRILQS
DDAGATFLLE QGAKHLVKDS HGRSCFELAA FYGLINTLRV ICGLGVNINE RTGGGLGYTV
LKHALSEGHY DCASLLVSLG CDLESVTADG SFIQTMLHHF IDAADEKAAV FLVQNGCNGD
ATRASRDSGD EKEETALHRA VASGLNELVA ALVIAKVNLN WQDAQGRTAC HIAVQEKNAE
ALSQLLKAND VSFLSIRDKL GQTPFSLAVV TKEHSLAAAI VERQPHVALQ TNGNGENLLH
TSVKSNDLES VLFLLSTHTD ATRVTTDGSK RSALHYAANV DNELILRNLI LAGCDVGLTA
ADGSTALHVA VRANRPVHAE ILLENGADPN LIDERRENAL LAAVRCGSVD CVKVLVAHAN
VDSLAVNKNA QSALHLCATL TGEKVPPRSS PAEICDLLLR REAGRLSDKD FGAFVDLRDA
DGNTALLLAY MAGNGDVCRC LLRGGATMGA RNADGATMFT YETPTRLLLF RLLDSLEREP
RWSDGDMCDC GIRFSITVRK HHCRHCGRLV CAKCSEVTMP IAKFGEEKRV RVCSLCAEVL
TTGGVR
//
