ID   A0A368G0U9_ANCCA        Unreviewed;       463 AA.
AC   A0A368G0U9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
DE   Flags: Fragment;
GN   ORFNames=ANCCAN_17903 {ECO:0000313|EMBL:RCN36217.1};
OS   Ancylostoma caninum (Dog hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN36217.1, ECO:0000313|Proteomes:UP000252519};
RN   [1] {ECO:0000313|EMBL:RCN36217.1, ECO:0000313|Proteomes:UP000252519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Baltimore {ECO:0000313|EMBL:RCN36217.1,
RC   ECO:0000313|Proteomes:UP000252519};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Ancylostoma caninum.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCN36217.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JOJR01000576; RCN36217.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368G0U9; -.
DR   STRING; 29170.A0A368G0U9; -.
DR   Proteomes; UP000252519; Unassembled WGS sequence.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR   PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252519}.
FT   REGION          44..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..175
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         463
FT                   /evidence="ECO:0000313|EMBL:RCN36217.1"
SQ   SEQUENCE   463 AA;  50303 MW;  2C7435E3B99562BD CRC64;
     MAAQHGGKRD VADDPVSQLK QSISKLTEGI QKMGVVLGAA QNDIIMSPKS SPDRTPNQSQ
     ATGKSASPSK GSQDVKSHDK DAQTSKEPKP APYNAEQHTT MSAEEKKAQR ANKAAEKKAR
     AEAAAAKKAA AAAGQSDAGS APKDQKKKPE RINNQNQKLS KAPTSSETSQ PNGDVNQIQN
     EATTHAPGKS ALRSDAKHQT AREVKFDLCA NVVKSASEES IGSDVPIGPV SECPDPPSTA
     HIHPAFLNLA VRCEQEMIDE VDTLCLNFIA AFKEYLADWS SQRQKENKDP SSLGHDLDLA
     IRPQIAHLTQ DSRWPLPYAL GNLVRQLKKE IIKTGTPDRS GRVQTADDIR KWLDDCEEEY
     FGSAYRAISD YLLGKMKTAP NVITYDWCPL VNKVLLDSIE RGFQTVFTVV DPEMEGRGLR
     HIKSFTERGI RCRYTDLNSV GAVMKNGSMV LLGCAAVLSN GCV
//