ID A0A368G310_ANCCA Unreviewed; 452 AA.
AC A0A368G310;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative tRNA (Guanine-N(7)-)-methyltransferase {ECO:0000313|EMBL:RCN37430.1};
DE Flags: Fragment;
GN ORFNames=ANCCAN_16682 {ECO:0000313|EMBL:RCN37430.1};
OS Ancylostoma caninum (Dog hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN37430.1, ECO:0000313|Proteomes:UP000252519};
RN [1] {ECO:0000313|EMBL:RCN37430.1, ECO:0000313|Proteomes:UP000252519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Baltimore {ECO:0000313|EMBL:RCN37430.1,
RC ECO:0000313|Proteomes:UP000252519};
RA Mitreva M.;
RT "Draft genome of the hookworm Ancylostoma caninum.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCN37430.1}.
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DR EMBL; JOJR01000469; RCN37430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368G310; -.
DR STRING; 29170.A0A368G310; -.
DR Proteomes; UP000252519; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0008176; F:tRNA (guanine(46)-N7)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_03055; tRNA_methyltr_TrmB_euk; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR025763; Trm8_euk.
DR InterPro; IPR003358; tRNA_(Gua-N-7)_MeTrfase_Trmb.
DR PANTHER; PTHR23417; 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE; 1.
DR PANTHER; PTHR23417:SF16; TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE; 1.
DR Pfam; PF02390; Methyltransf_4; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51625; SAM_MT_TRMB; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:RCN37430.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RCN37430.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT REGION 105..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 452
FT /evidence="ECO:0000313|EMBL:RCN37430.1"
SQ SEQUENCE 452 AA; 51233 MW; 90D9726EBC2B9993 CRC64;
MRTKKQGLRV VPPQIGCSRT IVGSGSYSNH EQKRMAGRFQ VGSDEPAEFV NVGIAQIVLL
SSLSKAKVDS YRLVRKISRP ELLGVGKPSR KNVVELRQEL LTKYHPPAAS TIPSSSKTNS
NEFSAPKNKK SKTKSSNSVD SRTVTLSPGY AYAHLAKPCQ HCGCKRVRVV NPGRLDRRNI
MECTNRECIA TIKFTNIPEG TLINPGGKPE EFSWYDLDPE EIFYPSTSTF ARLEESLKSD
VKKPFIPQIR YGEHGSIVVR CPGQKELVKM KQRAHSNPHS DHDIEYPRTP AEMDWKKLYG
DYAEGRQVEF ADVGCGYGGL LMKLSPMFPD VLMVGLEIRV KVSDFVQEKI KALRLRSTET
GGFRNVACLR SNAMKYLPNY FYKHQLSKIF FLFPDPHFKN KKHKWRIITP GLLAEYAYVL
RPGGLSIFLY QFVDSDSQSY WKDYCQSSLQ RA
//
