ID A0A368G3L0_ANCCA Unreviewed; 409 AA.
AC A0A368G3L0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Delta-like protein {ECO:0000256|RuleBase:RU280815};
GN ORFNames=ANCCAN_15057 {ECO:0000313|EMBL:RCN39023.1};
OS Ancylostoma caninum (Dog hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN39023.1, ECO:0000313|Proteomes:UP000252519};
RN [1] {ECO:0000313|EMBL:RCN39023.1, ECO:0000313|Proteomes:UP000252519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Baltimore {ECO:0000313|EMBL:RCN39023.1,
RC ECO:0000313|Proteomes:UP000252519};
RA Mitreva M.;
RT "Draft genome of the hookworm Ancylostoma caninum.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative Notch ligand involved in the mediation of Notch
CC signaling. {ECO:0000256|RuleBase:RU280815}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280815}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU280815}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00377}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCN39023.1}.
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DR EMBL; JOJR01000362; RCN39023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368G3L0; -.
DR STRING; 29170.A0A368G3L0; -.
DR Proteomes; UP000252519; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.10.25.140; -; 1.
DR InterPro; IPR001774; DSL.
DR Pfam; PF01414; DSL; 1.
DR SMART; SM00051; DSL; 1.
DR PROSITE; PS51051; DSL; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|RuleBase:RU280815};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00377}; EGF-like domain {ECO:0000256|RuleBase:RU280815};
KW Membrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280815};
KW Signal {ECO:0000256|RuleBase:RU280815};
KW Transmembrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280815,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 105..147
FT /note="DSL"
FT /evidence="ECO:0000259|PROSITE:PS51051"
FT REGION 158..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 107..116
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 138..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
SQ SEQUENCE 409 AA; 44411 MW; AB50481D85074922 CRC64;
MFLIRISSEE RHNVQYCFTE LPYTVRRTPN SRCLKSGELN VAKKTERVID LRLMNSTSAY
LAVEFSVTAG GQGPPKTITE RVVVDGALPA KRIAIASGLV LEFVTICDRP WYGLMCSRYC
IERSAANYVC DPRGEKVCLV GWTGKDCDIA TKNVFPTLSE ETDPPSSPVS TTLPSTGRLP
SQKHEPAVVK TTTSAGVTSF SASTISPTLA TTTELFIPKV SHPVPRFTTI RVTHRTRARS
VSSSTREAPA STVSSQSGNI EVLKIVSPAD GDNSTSSCIE TVITVFLVLI TSALLGYLLT
MCVRNSSVQN WINDRKAGIF APSSCTSSRK YNSQEPLKEV FVIGTKKADV KVDYESTEKL
GPRYSSEPTA AVSPSPSAND ESVVESNTYH EIDSFLVSSV VDLRIATLV
//
