ID A0A368G6Q7_ANCCA Unreviewed; 468 AA.
AC A0A368G6Q7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=VHS domain protein {ECO:0000313|EMBL:RCN38665.1};
GN ORFNames=ANCCAN_15422 {ECO:0000313|EMBL:RCN38665.1};
OS Ancylostoma caninum (Dog hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN38665.1, ECO:0000313|Proteomes:UP000252519};
RN [1] {ECO:0000313|EMBL:RCN38665.1, ECO:0000313|Proteomes:UP000252519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Baltimore {ECO:0000313|EMBL:RCN38665.1,
RC ECO:0000313|Proteomes:UP000252519};
RA Mitreva M.;
RT "Draft genome of the hookworm Ancylostoma caninum.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the STAM family.
CC {ECO:0000256|ARBA:ARBA00009666}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCN38665.1}.
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DR EMBL; JOJR01000383; RCN38665.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368G6Q7; -.
DR STRING; 29170.A0A368G6Q7; -.
DR Proteomes; UP000252519; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd03568; VHS_STAM; 1.
DR Gene3D; 1.20.5.1940; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR PANTHER; PTHR45929:SF3; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF02809; UIM; 1.
DR Pfam; PF00790; VHS; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 24..152
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 212..271
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 468 AA; 51066 MW; 725B38DCEF7AB06E CRC64;
MTSLLQMGIF GDSSSPFDEC IEKVTAEHLT TENWAMILDV CDKVNSDPRA PKNAILSIRK
RLNHRDPHVV LLALSVLDSC WSNCGPAFRK EVSSASFISE LQSKAVHSTR LIAEKTRMMI
QKWVENECKS DASLSLVVTL YKNLVADGHS FTSSEPKKSS ISRDIEAEEE DALARAIALS
LQESDKNTKT NKVYQSLNTT SFTSTNGTSN KTSERTVRAL YDFEAAEDNE LSFVSGDLIT
VTDDSNPNWW CGRIGVQQGL FPSSFVTSDL SEVKPETMST AAAAPAPAVT TIDESVLLRC
IQMLEDCDPT GDTPDPPELA KVEQASRAQG PLINARLAAI DSQVNALSQV DMAIRDVLAL
YDQAVQQAHY QASVYQAQAP VVNPGVLPAQ TAGISSNTAY QTSYANLPAQ TVPVSNVPVR
QDGQTQYAPV AQYAPVPQPA YQQPQIQPEW NQQPVQHPAP VQHPAQNY
//
