ID   A0A368GLN1_ANCCA        Unreviewed;      1142 AA.
AC   A0A368GLN1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Tetratricopeptide repeat protein {ECO:0000313|EMBL:RCN45281.1};
GN   ORFNames=ANCCAN_08677 {ECO:0000313|EMBL:RCN45281.1};
OS   Ancylostoma caninum (Dog hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN45281.1, ECO:0000313|Proteomes:UP000252519};
RN   [1] {ECO:0000313|EMBL:RCN45281.1, ECO:0000313|Proteomes:UP000252519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Baltimore {ECO:0000313|EMBL:RCN45281.1,
RC   ECO:0000313|Proteomes:UP000252519};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Ancylostoma caninum.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in endocytosis. {ECO:0000256|ARBA:ARBA00002550}.
CC   -!- SIMILARITY: Belongs to the YPP1 family.
CC       {ECO:0000256|ARBA:ARBA00038251}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCN45281.1}.
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DR   EMBL; JOJR01000105; RCN45281.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368GLN1; -.
DR   STRING; 29170.A0A368GLN1; -.
DR   Proteomes; UP000252519; Unassembled WGS sequence.
DR   Gene3D; 1.10.287.810; Mitochondrial import inner membrane translocase subunit tim13 like domains; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR004217; Tim10-like.
DR   InterPro; IPR035427; Tim10-like_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR045819; TTC7_N.
DR   PANTHER; PTHR23083:SF464; TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A; 1.
DR   PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR   Pfam; PF13432; TPR_16; 2.
DR   Pfam; PF19440; TTC7_N; 1.
DR   Pfam; PF02953; zf-Tim10_DDP; 2.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF144122; Tim10-like; 2.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          87..133
FT                   /note="Tim10-like"
FT                   /evidence="ECO:0000259|Pfam:PF02953"
FT   DOMAIN          132..196
FT                   /note="Tim10-like"
FT                   /evidence="ECO:0000259|Pfam:PF02953"
FT   DOMAIN          220..571
FT                   /note="Tetratricopeptide repeat protein 7 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19440"
FT   REPEAT          1059..1092
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1142 AA;  126450 MW;  3B934B24056FF9D1 CRC64;
     MMFPGGIGGS ELQQAAADKV KNDVGTFVLF GLLVEAGTCR CKFAHSGIRY YEKMVVSNKY
     DLVKCCVRLF VFIGAMDTDP QLARFLQQLQ SETQRQKFTE QVHTLTGRCW DVCFADYRPP
     SKLDGKTATC LQQLQSETQR QKFTEQVHTL TGRCWDVCFA DYRPPSKLDG KTATCLQNCV
     NRMIDASNFM VEHLQKMEGS KGMLCFHRIR LSFGSWTTHV MGNWKRLSEL LHSMKSKHSG
     MDDMVELVEA ELQLETFLEQ QGEVLRPRSD YANELREAEM LLKDTVDRRS GATTLEAHLL
     LAKLHYASAA YSEALKDIEN SGMELANTQF RTLRALRLVA EVYAIKGFCL EALESNDKGM
     GKMKSLFCYE KAAELAILYV GEIEKNIVGG SGKGSVTAST PTPTQKSEKL GDILECCLER
     VATLRVRDSA IERKSNVEGI EWYRRIITCL GDKSTGERLQ QKMSRQFAEL LLRAVPADGR
     GGAISQAVSM KTQNLSFYMG SHKGYFSPAS RTEEVILLLL ISEVLSTREV VLNRSADLSA
     SRHQSVRSAK SVYNLLTLVL STLRQYHLLS TVYERAMKFV NQDEYLWQQF ALSLVCRGKW
     LRAARVLEQC IAAGTKDGSQ ANHGGELDTG MSNTAMHHMQ AAVLHMEHLG QNDAAIRHAA
     AAVELCSEGP LSYLKGRAQL LCAIAHGRRA QYEPCFNDRR RLLAKALTMF ENCVHTDPHD
     YLAHYYCALY HAIVRDLEAA RERCARSLEL NPEQPAAIML LALIFTAEGD LKGALELVVN
     ALKDYPTHYG LLVLQLHIET KFGRIDESLD TCSHLLDFWR KRECCIEDER VQLSLSAADG
     QNMLRDASSV KAGTFLHDYG VRELVPSSYP LCIFLLFGEI ISFWATLAPF SYFVLAGTPS
     VGRELSSSTP IFANPLGIGL GTPIINPNVG SSQSGLDLAV SAVDSGVPAS EAGGQSASSE
     SGGAAGSASS ALWTRFKAQA NMWMALAELF LAEGRLNDVG PCVEQAVVLF PHAHQALYLK
     GRLFAAKADK ATDETVAAKF RSEANACLLS ALALCPSHTS SLFHLAKLYT SEGNIAMAEQ
     MYRELVRVDP LCCQWWQELG SCLMRRGNVT RAMECFAAAS QLDRSTPLLA FSSIPLVFPS
     SF
//