ID   A0A368GQ56_ANCCA        Unreviewed;       450 AA.
AC   A0A368GQ56;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN   ORFNames=ANCCAN_07490 {ECO:0000313|EMBL:RCN46496.1};
OS   Ancylostoma caninum (Dog hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN46496.1, ECO:0000313|Proteomes:UP000252519};
RN   [1] {ECO:0000313|EMBL:RCN46496.1, ECO:0000313|Proteomes:UP000252519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Baltimore {ECO:0000313|EMBL:RCN46496.1,
RC   ECO:0000313|Proteomes:UP000252519};
RA   Mitreva M.;
RT   "Draft genome of the hookworm Ancylostoma caninum.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCN46496.1}.
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DR   EMBL; JOJR01000078; RCN46496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368GQ56; -.
DR   Proteomes; UP000252519; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF90; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        46..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          303..378
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   450 AA;  51133 MW;  BC2B9CEF0E62F932 CRC64;
     MSEYLLDSIQ EGYTALDARS RHEFAVMCQF SGNSGQSLFF PLERSFFSYL AGIMKLIVVL
     MAKDGGSMHR KAHFDEAENI INDIYNLTVR SGERRMEYRR LCEPYCSSSK KLFVTFKKYF
     DVTYKSAVEY HYYSDSYNLS YPFGSIWGVR IPLEKALFGV RLVDSTNAPP PKTVKSSRWR
     RFFSERIPID PNKTIESQIT NMEHVSLMVL FLYGNKSTPS KTADLTSWEL GMYEWSRQVN
     QGEYRNHSLV KLLIFGTEIL NMEINTSNRK LAPYFGAGFS SMIGFVALCV FSSAYYYDAV
     DLGKILVGIG ATLCPLLAIT STYGVLCLMG SRINSLLFVM PFLIMGVGVD AAFLMVNSWQ
     KLTLRGYSNS ESYVEVRLFC FGTATSMGLT YVYQLILFGP VLSLAAGCEK KSRLEAKDYD
     GGWRKAVRSP NLPQHPSCCC FYLQYTWKII
//