ID A0A368GYN0_ANCCA Unreviewed; 581 AA.
AC A0A368GYN0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=PDZ/DHR/GLGF domain protein {ECO:0000313|EMBL:RCN48668.1};
GN ORFNames=ANCCAN_05307 {ECO:0000313|EMBL:RCN48668.1};
OS Ancylostoma caninum (Dog hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=29170 {ECO:0000313|EMBL:RCN48668.1, ECO:0000313|Proteomes:UP000252519};
RN [1] {ECO:0000313|EMBL:RCN48668.1, ECO:0000313|Proteomes:UP000252519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Baltimore {ECO:0000313|EMBL:RCN48668.1,
RC ECO:0000313|Proteomes:UP000252519};
RA Mitreva M.;
RT "Draft genome of the hookworm Ancylostoma caninum.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCN48668.1}.
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DR EMBL; JOJR01000044; RCN48668.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368GYN0; -.
DR STRING; 29170.A0A368GYN0; -.
DR Proteomes; UP000252519; Unassembled WGS sequence.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd11862; SH3_MPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR PANTHER; PTHR23122:SF42; MENAGE A TROIS, ISOFORM A; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000252519};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 139..205
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 228..308
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 348..561
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 308..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 64511 MW; 63921DD243D87409 CRC64;
MNNGEGKESH NDSNNFIGKF EAILHTLFEE YGKKPASPKN LTEDQKSIAR CLQELISSGE
LKIDKAASET TSLCDGFIGE WESTGIKSAA VQQLIALLNR PHVRGVLISA EDISSNRYLP
KLPSVPFEVD EDEGIVVKVV RIVKRDETLG ATIRNDHGKI YIARLIAGGV AARSACIQEG
DRILEVNGLP TSDLSIDDVA RILNRVDKGT VTLKLVPAEM STRTDNGTPH VYLRALFDYK
GKEDDRHPCP EVALSFKRGD ILELLACNDD HWWQARRIGS GAFAHCEDIK AASRIGLIPS
EVLQMTKSMS EIEQRPTDGR GSSRSGSSHE SEYVYESVCR LSPRDGISRI IVLLGPPGVG
RNELKRRLLS RYPQRFSTTV PHTTRPKRTG EVEGVDYYFT ERSVMEKMIY SGQMLEFGEF
RGIFQCLRFS PKLTRFPTGN LYGTALSSVR DAQQAGIPLI TPHPLALQLL RTHEFLPFIV
FIQPPDAATF KSTRVVNTSL PRGSSGQSRN ASVTRMFSDA EIEQVINGGA TLYKQYGHLF
DATIINKDLE ESTTQLLNLI SDVETKPTWV PLSWATNLCS E
//
