ID A0A368JRK2_9BACT Unreviewed; 700 AA.
AC A0A368JRK2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846, ECO:0000256|RuleBase:RU363016};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU363016};
GN Name=recG {ECO:0000256|RuleBase:RU363016};
GN ORFNames=DUE52_07965 {ECO:0000313|EMBL:RCR70290.1};
OS Larkinella punicea.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Larkinella.
OX NCBI_TaxID=2315727 {ECO:0000313|EMBL:RCR70290.1, ECO:0000313|Proteomes:UP000253383};
RN [1] {ECO:0000313|EMBL:RCR70290.1, ECO:0000313|Proteomes:UP000253383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zzj9 {ECO:0000313|Proteomes:UP000253383};
RA Zhou Z., Wang G.;
RT "Genome analysis of Larkinella rosea.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Critical role in recombination and DNA repair. Helps process
CC Holliday junction intermediates to mature products by catalyzing branch
CC migration. Has a DNA unwinding activity characteristic of a DNA
CC helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-
CC DNA). {ECO:0000256|RuleBase:RU363016}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363016};
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504, ECO:0000256|RuleBase:RU363016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCR70290.1}.
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DR EMBL; QOWE01000005; RCR70290.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368JRK2; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000253383; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR NCBIfam; TIGR00643; recG; 1.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363016};
KW DNA damage {ECO:0000256|RuleBase:RU363016};
KW DNA recombination {ECO:0000256|RuleBase:RU363016};
KW DNA repair {ECO:0000256|RuleBase:RU363016};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU363016};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363016};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363016}.
FT DOMAIN 285..448
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 474..632
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 700 AA; 80031 MW; 3D19C41F23145CF7 CRC64;
MTERVTFFDT KIDYLKGVGP QRASLLNTEL NIFTYRDLIQ YYPFRHEDRT RFTTIIELSE
ALPAAQVIGR IRDWAVIGEG PKKRLVAEFT DHTGSMDLVF FQGISHFEKF LRPGAEYIAY
GKPIAFGSKY SITHPELDPL TAENEQGSTF HPIYNLTEKL RRMRVDSKLI ARMMQQLLEI
AYPHIHETLP NSLLEKYRMI SKADAIENIH LPKSQAWLKQ AERRLKFEEL FYNQLRLIKN
KLIHKTEYPG QVFRNMTLLN RFYKEFMPFL LTDAQKRVLR EIHGDLVSGK QMNRLLQGDV
GSGKTIVAFI AMLMAIDNGA QACIMAPTEI LADQHYYGLK MFADQLGLTI GRLTGSTRTK
GRRIIHDQLQ SGMMHIIVGT HALLEDVVQF KNLGLCIIDE QHRFGVAQRA RLWNKNQEIY
PHMMVMTATP IPRTLAMTLY GNLDLSVIDE LPAGRKPIKT VHRYDTHRLE VFGFIRQQIE
QGRQIYIVYP LIEESEKLDF KDLMDGHESI TRAFPNHPIG VLHGRMTGYD KDFEMDRFVK
GETKIMVATT VIEVGVNVPN ASVMVVESAE RFGLAQLHQL RGRVGRGAEQ SYCILMTDYK
LSKETRTRIE TLVKTNNGFE IADVDLQLRG PGDLSGTQQS GIADLILADL AKDGAILMAA
RESAQQILDE DPDLILPQHA PIRNQVEMQR ADETNWSRIS
//
