ID A0A368MHA8_9FLAO Unreviewed; 646 AA.
AC A0A368MHA8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:RCT55442.1};
GN Name=mrdA {ECO:0000313|EMBL:RCT55442.1};
GN ORFNames=DUZ96_03905 {ECO:0000313|EMBL:RCT55442.1};
OS Winogradskyella sp. KYW1333.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Winogradskyella.
OX NCBI_TaxID=2282123 {ECO:0000313|EMBL:RCT55442.1, ECO:0000313|Proteomes:UP000253188};
RN [1] {ECO:0000313|EMBL:RCT55442.1, ECO:0000313|Proteomes:UP000253188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KYW1333 {ECO:0000313|EMBL:RCT55442.1,
RC ECO:0000313|Proteomes:UP000253188};
RA Yang H.G., Seong C.N.;
RT "Complete genome sequence of Winogradskyella aestuarii KYW1333 isolated
RT from seawater.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCT55442.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QPHL01000013; RCT55442.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368MHA8; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000253188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000253188}.
FT DOMAIN 46..209
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 250..575
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 646 AA; 73057 MW; 6ECB513C5A46D473 CRC64;
MRKLLLLTIV ILVGIVFIAR LFYLQVYGGY EYNVFEDSAI KKEYNYPKRG YVYDRNGKLL
VANQPSYDVM VIPRDVEPLD SIEIEEFCTH LKITKEDYFK KLDRATRYSP RLPSPFVAQL
SKIDYAVLQE KMRKYRGFYI QKRSLRLYQT TIGANVLGDI GEVNRSIIAK QPYYNMGDLI
GKQGVEKTYE KTLRGVKGIK FIQKDRFNKD IGPFQDGTLD TLPVPGKDIK ITIDSKLQAY
GELLMKNKRG GIIAIEPASG EILAMVSGPS YNPNLLVGRN RSKNFTKLYK DSIAKPLFDR
GLQAMYPPGS PFKTLNALIA LQEGVVNTTD KFSCSLGYRY GNRKMGCHVH RSPADMNLGI
YESCNAYFAN VYRKIMDKYD SPAEGMDIWS KHIKSFGLGN YLNNDLSVGQ PGKVPTAKTY
DRGYGKSKWY TTFTISNAIG QGEVLATPIQ LANMAAAIGN RGFYYTPHII KDIEGESIPE
NFTTPKYTTI DKQHFEPVVQ GMFDVYNKGT AKWVQIPGIE ICGKTGTAEN FAIINGEKTQ
LTDHSIFVAF APKDNPKIAI AVFVENGYFG SRFAGRMASL MIESYIKGEI SRTDMEDFVL
RHTLKHEYAK PYSDEPFGIN RQTTLETVSP EEYQNILQIK ANIPKE
//
