ID   A0A368N9Q2_9EURY        Unreviewed;       593 AA.
AC   A0A368N9Q2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=PDZ domain-containing protein {ECO:0000313|EMBL:RCU46986.1};
GN   ORFNames=DU504_06505 {ECO:0000313|EMBL:RCU46986.1};
OS   Haloplanus salinus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloplanus.
OX   NCBI_TaxID=1126245 {ECO:0000313|EMBL:RCU46986.1, ECO:0000313|Proteomes:UP000252189};
RN   [1] {ECO:0000313|EMBL:RCU46986.1, ECO:0000313|Proteomes:UP000252189}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 18368 {ECO:0000313|EMBL:RCU46986.1,
RC   ECO:0000313|Proteomes:UP000252189};
RA   Kim Y.B., Roh S.W.;
RT   "Genome sequences of Haloplanus salinus JCM 18368T.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCU46986.1}.
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DR   EMBL; QPHM01000001; RCU46986.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368N9Q2; -.
DR   OrthoDB; 15212at2157; -.
DR   Proteomes; UP000252189; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd06159; S2P-M50_PDZ_Arch; 1.
DR   Gene3D; 2.30.42.10; -; 2.
DR   InterPro; IPR001193; MBTPS2.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR008915; Peptidase_M50.
DR   PANTHER; PTHR13325:SF3; MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE; 1.
DR   PANTHER; PTHR13325; PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE; 1.
DR   Pfam; PF02163; Peptidase_M50; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        61..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        468..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        507..527
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        567..588
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          123..572
FT                   /note="Peptidase M50"
FT                   /evidence="ECO:0000259|Pfam:PF02163"
SQ   SEQUENCE   593 AA;  61958 MW;  77C585F1A40B9A8F CRC64;
     MNTLLWVLVG VLVYSLVAKA LQIRGYLPSA VRLQGPIATI HTRRGRALLT RLARPKRLWR
     AYSNVGVGVA LVIMAGMFAL LLVQALTILR NPPAPSAVNQ PQNFLVVPGV NDFLPLAVAP
     EIVFGLLVGL VVHEGGHGLL CRVEDIDIES MGVVLLAFIP IGAFVEPDEE SQGSANRGAR
     TRMFAAGVTN NFVLTAVAFA LLFGPVIAAV GVAPGVAVDG AYEGSPASVE GIDHGDRITA
     VAGANVTTER DLNDALLAAE ERTVAVEIDG ERTVRVERSL TVVGSVGGNP ANLTVEDDPI
     EVTAVNGTPV HTRGEFRAAV ADGTFARIET TAGERTIPVG AYITGVAPDG PLANASAPTN
     ATMIVTGIDG QRVTSSADLA RVLDGYQEGD RVTVRAYVDG EFETYDVRLG ENPRDGNGFV
     GVDIFPGTSG LLVTDFGVRS YPAGAYLELL GGSGGEGSAT FSGLTDSAFA LVYVALVLPL
     ASIVLGIPNF PGFTPAVTNF YVVQGPLAPL GDGVFILANT LFWAAWVNLQ LGLFNCIPGY
     PLDGGRILRM GAEAVVSRLP VSDSPRVVRT ITTSIGLTML ASLVLMIFGP QLL
//