ID A0A368NJC4_9GAMM Unreviewed; 307 AA.
AC A0A368NJC4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=inorganic diphosphatase {ECO:0000256|ARBA:ARBA00012146};
DE EC=3.6.1.1 {ECO:0000256|ARBA:ARBA00012146};
DE AltName: Full=Pyrophosphate phospho-hydrolase {ECO:0000256|ARBA:ARBA00032535};
GN ORFNames=DU002_11465 {ECO:0000313|EMBL:RCU49529.1};
OS Corallincola holothuriorum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Psychromonadaceae; Corallincola.
OX NCBI_TaxID=2282215 {ECO:0000313|EMBL:RCU49529.1, ECO:0000313|Proteomes:UP000252558};
RN [1] {ECO:0000313|EMBL:RCU49529.1, ECO:0000313|Proteomes:UP000252558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C4 {ECO:0000313|EMBL:RCU49529.1,
RC ECO:0000313|Proteomes:UP000252558};
RA Xia H.;
RT "Corallincola holothuriorum sp. nov., a new facultative anaerobe isolated
RT from sea cucumber Apostichopus japonicus.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:43474; EC=3.6.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000926};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCU49529.1}.
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DR EMBL; QPID01000006; RCU49529.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368NJC4; -.
DR OrthoDB; 9766150at2; -.
DR Proteomes; UP000252558; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004427; F:inorganic diphosphate phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR004097; DHHA2.
DR InterPro; IPR038222; DHHA2_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF22; MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE; 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02833; DHHA2; 1.
DR SMART; SM01131; DHHA2; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000252558}.
FT DOMAIN 180..306
FT /note="DHHA2"
FT /evidence="ECO:0000259|SMART:SM01131"
SQ SEQUENCE 307 AA; 33449 MW; FA223883F9A42D2E CRC64;
MPAYAVGHKV PDSDSICSAI ALSYLKTTIG EETLPARLGE LSPETLFILD KFGFEQPELK
MTFADTDGIY VVDHSDRIQG PDDIDDTTVL GIIDHHKLGD ITTSTPLECW IRPVGCTNTI
IKMMYDFHGV EIPKNIAGAM MCAILSDTVI FKSPTCTTAD IKCVEALAEI AGIEDYKALG
MEMFTVKSSV EGTPVRELVL RDFKDFKMGD NVIGIGQLEV IDLALFDEMK ADLQADIAAV
KEEGDRHSVL LLLTDIMKEG SELLVASDDA ALVEKAFGKS LVDGKAWLDG VMSRKKQVVP
PLQDAFA
//
