ID   A0A368NRA8_9GAMM        Unreviewed;      1025 AA.
AC   A0A368NRA8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:RCU52453.1};
GN   ORFNames=DU002_00335 {ECO:0000313|EMBL:RCU52453.1};
OS   Corallincola holothuriorum.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Psychromonadaceae; Corallincola.
OX   NCBI_TaxID=2282215 {ECO:0000313|EMBL:RCU52453.1, ECO:0000313|Proteomes:UP000252558};
RN   [1] {ECO:0000313|EMBL:RCU52453.1, ECO:0000313|Proteomes:UP000252558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C4 {ECO:0000313|EMBL:RCU52453.1,
RC   ECO:0000313|Proteomes:UP000252558};
RA   Xia H.;
RT   "Corallincola holothuriorum sp. nov., a new facultative anaerobe isolated
RT   from sea cucumber Apostichopus japonicus.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCU52453.1}.
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DR   EMBL; QPID01000001; RCU52453.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368NRA8; -.
DR   OrthoDB; 9757940at2; -.
DR   Proteomes; UP000252558; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252558};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        338..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        438..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        468..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        867..887
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        894..914
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        920..941
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        969..985
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        991..1015
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1025 AA;  112344 MW;  0CA45929F34ADB4D CRC64;
     MNIAQYTITK RTSVWVLMLM TLLGGYLSYQ NLGRFEDPEF VIRQAVIVTH YDGATAQEVA
     DEVTDLIEGA VQSLQELKEV ESVSRPGVSQ VTVEMDMAFA KSDADLQQIW DKLRRKVSDV
     QNQLPPGAGP SIVNDDFGDV YAQFYAITGE GFSDKQLQDY VDNIRRELAL VPGVARTTTL
     AEKQEAIFVE FARERLAQSG ISMEQIFDVL AQQNRVTVAG TITTENMRVP VIPASNFQST
     DELKNLHLTI GSDNTVIRLG DIANVTRGYQ EPFNQLMRYN GERAIGLGIS NMAGGNVVTM
     GDAVKARLAE LEDQRPLGIE LHEVSLQSDS VRDSVADFVI NLMMAVVIVF CVLLIFMGAR
     SGVIIGFVLL LTVAGTLCIM LFDGIAMQRI SLGALIIALG MLVDNAIVIT DGIQVRLREN
     PNLDRKQAVK EVVSATQWPL LGGTLVGILA FSAIGLSPSN MGEYAGSLFW VILYSMILSW
     LFAITITPML CHDFLEANDK SKSSQGDESK SVEDKPSALM NRYKALLEWV LQHRKLTLAV
     ILGVLFTAVY ALRFVPPGFM PESQRPQFVV DVYLPQGSDI HRTEKVMAAM EQDVLAKAGV
     TNVTGFIGGG GLRFMLTYSP VSANPSYGQL LVDVDDFHRI SPLLAELQGE LNASYQDASV
     MVWKFVLGPG GGKKIEAGFR GPDSQVLRQL AEQAKAKMIA NPNLIAVQDD WRQQVPVLQP
     VYAPDQLQRF GLTSHDVNQA IAQTLTGRNV GVYREGNDLI PIIARSPEHE RDRQQAIENT
     QVFSVKTGRF IQVSQLIESL DVVWQDDVLK RFERVPTIMA QADPAPGILT AEAFASIRDE
     IEAMPLPPGY SLDWFGEYKD AKEADEAIAI SAPYGFAAMV LIVVLMFNGV RQALVIWLTV
     PLAVIGVAVG LILFQTPFEF MATLGFLSLV GMMVKNAIVL VDQADQDIQA GIEPYLAVIK
     AATSRARPVA LGACTTILGV APLLADPFFK SMAVTIMFGL LFATVLTLVV IPLFYSMIFR
     VKIPA
//