ID A0A368PGQ0_SETIT Unreviewed; 1098 AA.
AC A0A368PGQ0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=SETIT_1G025400v2 {ECO:0000313|EMBL:RCV04743.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV04743.1};
RN [1] {ECO:0000313|EMBL:RCV04743.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV04743.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV04743.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV04743.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CM003528; RCV04743.1; -; Genomic_DNA.
DR RefSeq; XP_004951371.1; XM_004951314.1.
DR AlphaFoldDB; A0A368PGQ0; -.
DR GeneID; 101768021; -.
DR KEGG; sita:101768021; -.
DR OrthoDB; 991910at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF105; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 689..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 760..1036
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1059..1098
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1098 AA; 121405 MW; 0FFF971F160FC400 CRC64;
MRAQKNPRSN PEAAAPGQNQ QSLAVEREAS VALAHTQTSR RRRLPTRELA RLVAASPSSS
VVAATTASEE RRGREGEVMG PARGGVMALV RLLLLLLLGL GCSNGGRCSS AQTLLPPQEV
EALKGIANKL NKTDWDFSVD PCSASGNWIN SDGFLFSNVT CDCSFKNRTE CHIISLELMR
QNLSGVLPEE VVNLTYLRYL DLSRNFIQGP IPASWGDLPV YNLSLQGNRI SGTLPKELGR
MPMLKSLQLE GNEIEGPIPP ELGNISTLER FFISANNITG ELPSTFSRLT NMTDFRVDGN
RISGKIPSFI KNWQSVNRID MQGTSMSGPI PPEISLLKNL TELRVTDLSG PSMKFPPLQN
ALHLTEVVLR NCSIYGEIPS YLGRMQYLKV LDISFNKLTG QVPANFGGMM ALQYLYLTDN
MLTGDLPAWM LKNKASNKVN MDISYNNFTG NPPSECQQAN VNMVSSFSSS NDNSLQSCLR
KNLPCMGKSH YSNLFINCGG KTVVVNGVTY KDDSYQIGTS SFVLSDDKKW AYSSTGDFVG
NENADYIARN TSKLTMAYPE LYTEARLSPL SLKYYGLCME NGEYTVKLHF AEIVFTDDHT
YSSNGKRVFD VFIQGAKVLG DFNIKDEAGG AHRAITKTFA ANITDNTLEI HLYWGGKGTT
AIPYRGVYGP LISAISVTHT RRNHHGVSIG VVIAIVIAVT CLVIILMFIA FYFKVFQRMN
AKGKGRHSFY KGRKTNTSEL QTRAQYFFSM KEIESATRHF DPANKIGEGG FGPVYKGTLS
DGTTVAVKKL SSKSSQGNRE FLNEIGIISA LRHPNLVRLF GCCIDGDQLL LIYEFLENNS
LGRALFGRSE HQLKLDWPTR YSICLGTAKG LFYLHEESTL KIVHRDIKPS NILLDEKLQP
KISDFGLAKL NDDCGRVSTR IAGTVGYMAP EYATRGCLTR KADVYSYGVV ALEIVSGMSN
INSMSNEEYL HLLDWAERLK QQGKLLEMVD QRLGSEYSQE QALRLLNIAL LCTNTSPTQR
PRMSSVVKML CGQIPIEVVP DDDDLSEDLR LNIARSHSSM NNSKTDWSEM PSSDPSILLH
NSKDSGYLPS SSSSSLKL
//
