ID A0A368PZJ2_SETIT Unreviewed; 5068 AA.
AC A0A368PZJ2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=UBR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SETIT_2G154800v2 {ECO:0000313|EMBL:RCV11023.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV11023.1};
RN [1] {ECO:0000313|EMBL:RCV11023.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11023.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV11023.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11023.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UBR4 family.
CC {ECO:0000256|ARBA:ARBA00009970}.
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DR EMBL; CM003529; RCV11023.1; -; Genomic_DNA.
DR RefSeq; XP_004956401.2; XM_004956344.3.
DR STRING; 4555.A0A368PZJ2; -.
DR GeneID; 101780057; -.
DR KEGG; sita:101780057; -.
DR OrthoDB; 10597at2759; -.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19681; UBR-box_BIG_like; 1.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR025704; E3_Ub_ligase_UBR4_C.
DR InterPro; IPR045189; UBR4-like.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR003126; Znf_UBR.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR21725; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR PANTHER; PTHR21725:SF1; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR Pfam; PF13764; E3_UbLigase_R4; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 1535..1606
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT DOMAIN 2571..2630
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT ZN_FING 1535..1606
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 1493..1528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2799..2818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3103..3139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3793..3825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4852..4882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4925..4950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4979..4998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1499..1526
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3119..3137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3793..3813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4929..4950
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4983..4997
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5068 AA; 563547 MW; B37889109F3B6895 CRC64;
MAAAAEISAM LNHLAASAER DPPARRLRSP TARPGLEALA GALAAGPPTD PAAARAVLSA
ARAVVSAVLP TSVEEVESIA VEIVERSLEF CLLHLEKSSY ACDDFSLVNE VACFVEFILL
KGTHNKAYSL EPCVINDIIE QWTSVQVEAE RLSPQEKYFC YLKGFNCSKS GDDLKRFRLA
LLPEYLRQDY VISENTQSCS VVSPNSMVPL AQHFAAVHLC CIPRLLTLVG KLCQSPALEM
VEDVNINLRL SFTQRILKLV CGLTMEFPPD ASDAMMLSSV ARCADSLPAL FRLKFKFSNH
DRVFCVDGVG TILLQILEEF LQLMQIIVCN SDICCTVQVC VLSSMLEIFS PNIWRYERSG
TCLVPPLAYS PRVVQFVLKL LKDTKRWTRR VDRDKPDKDA FYYSFNHELN DLSCHVRSEE
VPLLKKYTCE EYLQFIFPSG EQWLNGLVHL TFFLHDEGVK SVTSEKPQLS CTKQPIVSEL
ESVASHEEEA LFGNLFAEVR PAGITESVEQ PTSLGSDLSN SQQGPIQLAA DLICFMKASI
FSPEWSRAIY MDACRKFNTC HLDQFLSILK CQACFPDESS TGNTMSSENK LLHINAACFE
LLQMFLVCDE CPASLREDLV EKVFNVDNGK YTYNHYALAL VAHAMTYAAN SGFSLGRKIF
VQYVTYLLEK ANDTSSSSLN VSDFCASLPC AFHLEILLAT FHLTTESEKA DLVKIVLSSL
EKMKKPPSGV SVTGLTRWAL LLSRLLLVLR HMLLYPLTHP SWLFMRMRSR LRDIQLNQGQ
SHSMNDCLPS LATVIVEEML DDSVKKSAMA SDLLPHLIDM TPTHADSYFD KAAVETLGLS
LADLGATMSQ ILNSWNGRSA EVADDLIVER YIFFICWNTL SVTGCHGNGS LLNDDYLKPE
LGNVNVFLAF ALSISNGASS HAGIDLPALI FELLELLHSD ILGSSKLESW DFPRKGAWLS
FILSLINADL QRQQVQVGAE TEVDSHRKHE VQGEELFTHG NSLSIYLTKN IGRCLDTLSS
LLEVYLHTFK KAYLSFLYSG KPSLDNSYPS LLLKHSVFDK SKHHLLFEKS GSYLEMLEPI
YQLSSRIDGV TTKLGEGQEN YFSLKCLLHG FPSAYPSSNS ALLSCILVIN EIMQTFNGYT
KVALPGDRDR VDEGIISKLL SMVMAVRSDQ TFKPIHGECD NIFMSLINNR DDLAKYSDLF
VLKQLEGFLA DINSNESMDS RMKEILVSTI VDLVEDLRSK REVFKFFLGD DAEGAPDEAS
RIFASEHADM SVFLDVLDCK SEQVNLKILH LLTDILRNGC CPGLKQKLQN KFIGMDVPCF
SSWLEFVILG PSVKVESTNG TAGPATRELA VDFFTNLICP SPEAVTKELQ HHLFNSMLLL
LDRAFLSHDL QTAKAYFHFL VQLSSEESHF KHLFEKTLIL METMVEDKGK LHTLKFLFSF
VEAVFGDTGL NRSALKRLSS KTSGSSFGSG SLIPKQLKNS ENLVIRTNQV SNPAVDCDAS
SGEEDEDDAT SDGELGSIDR DEEDDGDSDR ALASKVCTFT SSGSNFMEQH WYFCYTCDLT
VSKGCCSVCA KVCHRGHRVV YSRSSRFFCD CGAGGVRGSS CQCLKPRKFT GSSTVPPAAS
SFHPILAYHE DVEQVADSSS DFEDDISTDA DSSMKLSVPN EFSSGLPLFL KNLDIEVKVL
EICKKLLPAI LDRRELNLSK DRKVLLGGDV LVSHSSDIFQ LKKAFKSGSL DLKIKADYPN
SRELKSHLAN GSLAKLLLSI STRGKLAVGE GDKVAIFDVG QIIGQPTASP ITADKTNVKP
LSRNIVRFEI VHLVFNPLVD HYLAVSGYED CQVLTLNSRG EVTDRLAIEL ALQGAYIRRV
EWVPGSQVQL MVVTNLFVKI YDLSQDNISP MHYFTVADDI IVDATLVPSS MGKLVLLVLS
EGGLLYRLNV TLEGDVGAKI LAETVLVKDA VSMHKGLSLY FSSTYRLLFV SHQDGTTFMG
CLNADSSSIT ELSYICEEDH DGKSKPAGLY RWRELLAGSG ILTCLSKSKS NAPFAVSLGP
HELVAQNMRH SIGTNSSVVG VAAYKPLSKD KTHCLILYDD GSLHIYSHTP NGGESSTILA
AEQTKKLGSS ILSSRAYTGI KPEFPLDFFE KTTCITSDVK YNSETTKSGD SESIKQRLTS
DDGYLESLTS AGFKVTISNP NPDIVMVGCR IHVGNTSASN IPSEITIFHR VIKLDEGMRS
WYDIPFTTAE SLLADEEFTI SVGRTFDGSS IPRIDSIEVY GRAKDEFGWK EKMDAALDME
ALGGSSTGGR SGKRPQIVQA APIQEQVLAD ALRILSRIYL LCPPSCFTDM ADAGMELNNL
KCRALLETIF QSDREPLLHS AACCVLQAVF PKKDMYYHVK DMMRLLGVIK SLPAITSRIG
VGGAASSWVI KEFIAQIHTV SKVALHRKSN LASFLETHGT ELVDGLMQVF WGILDLDRPD
TQTINSLVVP CVEFIYSYAE CLALHSNENS GVSVGPAVAL LKKLLFAPYE AVQTSSSLAI
SSRFLQVPFP KQTMIANDDA PENHAKPSAS AMGSSSGNAQ VMIEEDPASS SVQYCCDGCS
TVPILRRRWH CNICPDFDLC ETCYEILDAD RLPVPHSKDH PMSAIPIELD TFGGEGNEIH
FSIDELTDSG VLHPPADRSV QTSPSSIHVF DASESADFPE TIAGQTTVSI SASKRAINSL
LLSHLIEELR GWMGTTAGTR AIPLMQLFYR LSSAVGGPFM DSSKPENLDL EKFVKWLMDE
ININKPFPAK TRCTFGEVSI LVFMFFTLMF RNWHQPGSDS SHSKSSGSSD LTEKGPVQVP
ASTTVALPSS RGDQDKNEFA SQLVRACSAL RQQSFLNYLM DILQQLVHTF KSSSINGEAG
SSGSGCGSLL TVRRELPAGN FSPFFSDSYA KSHPTDLFTD YYKLLLENTF RLVYSMVRPE
KEKSAEKDRS NKVPNTKDLK LDGYQDVLCS YISNPHTSFV RRYARRLFLH LCGSKTHYYS
VRDSWQYSHE VKKLHKIVNK SGGFRNPVPY ERSVKLIKCL SILCDVAAAR PKNWQKFCLK
HMDLLPFLVD NFYHFSEECI IQTLKLLNLA FYSGKDANHN AQKPECADLG GSTRTSSQSS
DSKKKRKVDD GSEGSSEKSC MDMEQVVEMF NDKEGDLLKR FIDIFLLEWN SAGVRHEAKC
VLFGVWYHAK NPLRETMLTI LLQKVTHLPM YGQNIVEYTD LMISLLGKVN DSSAKQNDSE
LVNKCLAPEV ISCIFDTLHS QNELLANHPN SRIYNTLSCL VEFDGYYLES EPCVTCSCPD
VPYSRMKLET LKSETKFTDN RIIIKCTGSF TIQSVTMNVY DARKSKSVKV LNLYYNNRPV
TDLSELKNNW TLWKRAKSCH LTFNQTELKV EFPIPITACN FMIELDSFYE NLQASSLESL
QCPRCSRSVT DKHGICSNCH ENAYQCRQCR NINYENLDSF LCNECGYSKY GRFEFHFMAK
PSFSFDNMEN DDDMRKGLAA IESESENAHR RYQQLMGFKK PLIKLVSSIG EQEIDSQQKD
AVQQMMVSLP GPTCKVNRKI ALLGVLYGEK CKAAFDSVSK SVQTLQGLRR VLMTYLHQKS
SSDTNALPAF SIPRSPSSCY GCSTTFVTQC LELLQVLSKH ANCRKQLVSS GILSELFENN
IHQGPRTART LARAVLSSFS ESDADAVQEL NSLIQKKVMY CLEHHRSMDI AQSTREELLL
LSETCALVDE FWEARLRVAF QLLFSSIKVG AKHPAISEHI ILPCLRIISQ ACTPPKSDGD
KESGLGISSL ALQSKNDDTT GNTTTNNPSA KIQPDISGKV HDGSQRGQDI PLLSYSEWEG
GASYLDFVRR QYKVSQAVKG SIQKTRHDSH KPDYLVLKYG LRWKRRACRK SSKSDFSKFA
LGSWVSDLIL SSCSQSIRSE ICTLISLLCP SNSPRQFQLL NLLMSLLPRT LSAGESAAEY
FELLGIMIDS EASRLFLTVR GCLTSLCSLI TKEVSNVESQ ERSLSIDISQ GFILHKLVEL
LNKFLEIPNI RARFMSDRLL SEVLEAFLVI RGLVVQKTKL INDCNHLLKD LLDSLLLEST
ENKRQFIRAC ISGLQKHVKE KKRRTSLFIL EQLCNLICPV KPEPVYLLIL NKAHTQEEFI
RGSMTKNPYS SVDVGPLMRD VKNKICNQLD LIGLLEDDYG MELLVGGNII SLDLSISQVY
EQVWRKHHGQ TQHSLSNANS LTAASSIRDC PPMTVTYRLQ GLDGEATEPM IKELEEEREE
SQDPEIEFAI AGAVRECGGL EIILSMIQSL RDDEFRSNQE ELASVLNLLK YCCKIRENRC
ALLRLGALGL LLDTARRAFS ADAMEPAEGI LLIVESLTME ANESDISIAQ SVFTTTNEET
GAGEEARKIV LMFLERLCHP SGAKKSNKQQ RNEEMVARIL PYLTYGEPAA MEALIQHFEP
YLRDWTEFDQ LQKQHEENPK DDSISRNAST QRSAVDNFVR VSESLKTSSC GERLKEIILE
KGITKAAVEH VKQSFASPGQ TGFRTSAEWT SGLKLPSIPP ILSMLKGLAK GHLPTQKCID
EEGILQLLHA LEGVPGENEI GARAENLLDT LANKENNGDG FLGEKIQELR HATRDEMRRR
ALKKREMLLQ GMGMRQEFSS DGGRRIVVSQ PTIEGLDDVE EEEDGLACMV CREGYTLRPT
DMLGVYAFSK RVNLGATSAG SGRGDCVYTT VSHFNIIHYQ CHQEAKRADA ALKTPKREWD
GATLRNNETL CNCIFPLRGP SVPLGQYTRC VDQYWDQLNS LGRADGSRLR LLTYDIVLML
ARFATGASFS TDCKGGGRES NSRFLPFMVQ MASHLADGSA NQQRHAMAKA VTTYLSSSPS
TPESPIRLSA SISGPRGSSG SSEETVQFMM VYSLLSESYE SWLQHRPAFL QRGIYHAYMQ
HKHGRSTLKM SSDSSSSAVR SDEGSSSDMS ENKKLFTIVQ PMLVYTGLID QLQQFFKKGK
SSGMGKSGER EESGGSLEKW EIQMNEKLSN MKEMVGLSKD LLSWLEDMTS SDDLQEAFDV
MGALTDVFSS GHATCEDFVR AAIHAGRS
//
