ID A0A368PZJ4_SETIT Unreviewed; 1610 AA.
AC A0A368PZJ4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SETIT_2G169100v2 {ECO:0000313|EMBL:RCV11226.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV11226.1};
RN [1] {ECO:0000313|EMBL:RCV11226.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11226.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV11226.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11226.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003529; RCV11226.1; -; Genomic_DNA.
DR STRING; 4555.A0A368PZJ4; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF988; OS06G0707733 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 14..100
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 429..641
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 161..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1610 AA; 179662 MW; 9F9D57317E71C71C CRC64;
MAELGIEAAR WMVGKALGPA SSGLLEAWAA STELGTNIEN LRMELLYAEG MLNNARDRDR
GSGPEIQNPA LSELLQKLRG LAYRADDVLD ELEYFRIQDE LDGTYHAADE HGGGCLHNNA
LNARHIARNI RKMLGFSYGS GGSATRDEPA DEDTRGVSCG AWPCLGPKTP DDDNDEQEED
ASRGVLCRAV WPCGRASSKP PMPPVDRGDQ EVASGCMSRL ATAATAKISG FSKCSRGSAD
HNQSHEEKED ASRGVLCGAV WPCARASSST PPPNQDQEAH DGCMDGLISG VRGTINTVGK
HLPSYSVSHA QNVGNSNVAS TTGGRFLSSA ARPIEAPQRE GFVQTPKLKF DRVEMSRKMQ
EIVEQLKPLC AKVSAILNLE FLAANCRASQ RMATIRPITT SEPIEPQLNA REKETSNIIR
DITKGEYCDK DLTVLPIVGP GGIGKTTLTQ YIYNDEDLKN HFEVKLWVCV SVSFSMHRLI
QEIADKLPKD ENNSGDKKIE EQLKSKSNED EWKSFLVPFR KGQTKGSVIL VTTRFPAVAQ
IVKTTDQWID LNGLDNKEFE KFFFACVFGD MEETERPSEL VDIGNIIVGK LKGSPLAAKT
VGRLLRKHLD KDHWTRVLES KEWESQNGDH DIMPALKLSF DYLPFHLQQC FIYCALFPED
YKFGKQELIH FWIGLDVLHS RGENKSIEVI GLNYLTELVN HGLFKREEDA DGNTYYIIHD
LLHELARKVS ADECLSICSS NNLRSLQIPQ SIRHLSINID ESSVKDRKTF DICKEGFSVL
GKKLKFENLH SLMLFGEHQG SFVKTFRGLF SKAKAIRVIF ISGGNHSVED LLHNFSNLVH
LRYLRIAGSQ TPKDISRFYH LRVVDIKECR SSYDLPRHMG NLLKLRHFLV PDDEMHASIF
EVGRLKSLQE LRRFEVRKES KGFELTQMGH LLELCGSLSI DSLEKVEGRE EADEAKLMQK
KHLQELILIW NDTQSNKDDR AREEHVLEGL KPHSNLLKLS ITGHGGATCP SWLGVNLSVE
NLESLCLDYV AWKVFPPIGE FQLVNGAAKE ISSNIPGQHF KNLKRIELVH LARLQRWVVG
SSDQLLSHLE ELIIRICPEL VELQFSNSTC SEQEQKTTFP RLQELTISCC PKLVSLPPVP
WTSSLRNVRI YRVGLDFGSV RYWNDRRDHT MRIEGKGRAQ DMTVSFWTVL GFDKLTGLES
LVIRRNCPLL PLDVLQKLSS SIKFLDLSDC NMFSGKDIGQ MLSCMPQLSD LSIYRCEKIT
GFGVVEQLEE GKEEIATDGL LLLPPQLQRL QIRRCPELSL RPDSPHGGEK GGGLQGLTSL
VSLRVRECPK FLVSPWPSSS CFPFPTSLQY LNLSRMETLA PLSNLASLTE LSIARCGDLG
GADLGHLLAN GCLRKLSVYQ TPNFFSIECS EEPLESEMLQ LQSLETDDVA SVLAAPICRL
FSSSLTSLSI LMGDMERFTK EQDEALQFLT SLKRLQLYCR KLQCLPAGLQ KLANLETLVI
PGTPAIIHSL HRGSLPDSLQ ELLITGGGFH LPNSLRKLSI YNCSAIRSLP KESLPNSLQE
LEIDSCPAIR ALPKGGLPSS LQILDVRDGN SEDLRRQCRK LIGTVPVVRA
//
