ID   A0A368Q089_SETIT        Unreviewed;       945 AA.
AC   A0A368Q089;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN   ORFNames=SETIT_2G176700v2 {ECO:0000313|EMBL:RCV11329.1};
OS   Setaria italica (Foxtail millet) (Panicum italicum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX   NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV11329.1};
RN   [1] {ECO:0000313|EMBL:RCV11329.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11329.1};
RX   PubMed=22580951; DOI=10.1038/nbt.2196;
RA   Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA   Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA   Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA   Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA   Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA   Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT   "Reference genome sequence of the model plant Setaria.";
RL   Nat. Biotechnol. 30:555-561(2012).
RN   [2] {ECO:0000313|EMBL:RCV11329.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Yugu1 {ECO:0000313|EMBL:RCV11329.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   EMBL; CM003529; RCV11329.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368Q089; -.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF944; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT   DOMAIN          200..349
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          742..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..861
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        753..769
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        812..830
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        839..857
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   945 AA;  105323 MW;  1B7D558325701967 CRC64;
     MLAVETLVAI AVAKIVAQKL ASCSLPPLKV YCCSLFCNFR DDLRDLEKEL LCLEAQLKEK
     DKWLFGIEVA DEAQTVLAQS WHRDAKQLAF EIEDTIDEFV CSEEFYHEST CAHKASLLCS
     YSNPIAARVW TVKRMISETK KLNSAIKLNE RYGTGPAGTG LESRKFAEKE TTSYDGPDEV
     IGRATDLEAI VDTIKEQAKR LSIIAIVGPV GVGKTCLARL VFNHLDSGSR FHRRIWVYVH
     KSCSRVDIKR IGRQVVSQGL LVGEERPSAD YTMQEITTKV HEILKRERCL IVLDGLWGTD
     DDVHSLKQMF TSCSEDTESV IMVTTHNEQI AQHMSTLPLY RLAPMLEGDY CSDIFVSALR
     GRNSLFPRYR KEIISRCEGV PLVADFLGSI VRSGGWNQRA VWENARDKDL WKLEEDYAAT
     LSKELTLFAP FRLMFYNIPH GLRLCFAYCS VFPKGSRIHK RKLIQQWISL NMVEPATHGS
     VTAEMNAENI IKQLKAIHLL QVDNHAEGSS GATGEVLRMH YMAYELARFT SNKDILVVLE
     GEEAAVSSFP QERDEANRTC CFSQEKEQTS LTYCDHRYAQ LPVFTKHRPQ KVRSLILIPT
     TNLQEHKPVI PVAVSEVISG NKYLRVLDLS GCGITELPAC VCQLKQLRYL DASNLDMKEL
     PCVDNSLRKL VYLNLQVCRN LRRVHESFGM LSSLKYLNLA LCVGLTKLPA SFKRLRSPRQ
     DCTIDLSGCQ ESVVLQFNSE LQGDQTQPNQ VPDPQPDQLP QPDKVPNPQP IQPAISSTED
     KITGSHPGLL LESTSLVDLA DEQEESQPSP ETNRGHRASL SSSDSTFGDP YDGKTTGMKG
     AVGSSTSLQS SLVESAKRHA NGTKVHQPIE NLAQSPGGCQ DLEGTSQGPK KAINIAAEKI
     HVVITSNQHG DLQIPPKLES STSSVDANGS KLEYIMEVPF HLGAY
//