ID A0A368QJL4_SETIT Unreviewed; 999 AA.
AC A0A368QJL4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SETIT_3G275800v2 {ECO:0000313|EMBL:RCV18131.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV18131.1};
RN [1] {ECO:0000313|EMBL:RCV18131.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV18131.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV18131.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV18131.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM003530; RCV18131.1; -; Genomic_DNA.
DR RefSeq; XP_004962385.1; XM_004962328.1.
DR AlphaFoldDB; A0A368QJL4; -.
DR GeneID; 101762672; -.
DR KEGG; sita:101762672; -.
DR OrthoDB; 5490251at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR NCBIfam; TIGR00930; 2a30; 1.
DR PANTHER; PTHR11827:SF100; CATION-CHLORIDE COTRANSPORTER 1; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..622
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 664..785
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 796..998
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 109564 MW; 26483BBA57DA6B58 CRC64;
MENGGIEEAD DALPVPAPPN GRRYRPVGSS DRAVVQMTSM EPGSSSSAAI DAVVTPQPPR
NLKPDANLTI DPSMREGSPD DHATSGGSQG DSKLELFGFD SLVNILGLKS MTGEQIQAPS
SPRDGEDVAI TIGRPKETGP KFGTMMGVFV PCLQNILGII YYIRFTWIVG MAGVWQSLVL
VSFCGACTFL TGISLSAIAT NGAMKGGGPY YLIGRALGPE VGVSIGLCFF LGNAVAGSMY
VLGAVETFLD AVPSAGLFQK SVTVVNNTLV NGTETAGTST ISTPSLHDLQ VYGVIVTILL
CFIVFGGVKI INKVAPAFLI PVLFSLLCIY LGVFIAPRHN APKGITGLSI TTFKDNWGSD
YQRTNNAGVP DPSGSIYWDF NALVGLFFPA VTGIMAGSNR SASLKDTQRS IPIGTLSATL
TTTAMYLFSV LLFGALATRE ELLTDRLLTA TVAWPAPAVI YIGIILSTLG AALQSLTGAP
RLLAAIANDD ILPVLNYFKV SEGSEPHAAT LFTAFICICC VVIGNLDLIT PTITMFFLLC
YAGVNLSCFL LDLLDAPSWR PRWKFHHWSL SLVGALLCVV IMFLISWSFT VVSLALASLI
YYYVSIKGKA GDWGDGFKSA YFQLALRSLR SLGANQVHPK NWYPIPLVFC RPWGKLPENV
PCHPKLADFA NCMKKKGRGM SIFVSIIDGD YHELAEDAKT ACRQLDAYID YKRCEGVAEI
IVAPTMSDGF RSIVQTMGLG NLKPNIVVMR YPEIWRRENL TQIPSTFVSI INDCIIANKA
VVIVKGLDEW PNEYQRQYGT IDLYWIVRDG GLMLLLSQLL LTKESFESCK IQVFCISEED
TDAEELKADV KKFLYDLRMQ AEVIVVTMKS WESHMESSST VAQQDDSHEA YTSAQQRIRM
YLDEMKETAQ RERHPLMENG RQVVVNEQKV DKFLYTMLKL NSTILRYSRM AAVVLVSLPP
PPLNHPSYFY MEYMDLLVEN VPRMLIVRGY TRDVVTFFT
//
