ID A0A368QM04_SETIT Unreviewed; 1528 AA.
AC A0A368QM04;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SETIT_3G347000v2 {ECO:0000313|EMBL:RCV18981.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV18981.1};
RN [1] {ECO:0000313|EMBL:RCV18981.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV18981.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV18981.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV18981.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003530; RCV18981.1; -; Genomic_DNA.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1135; OS08G0246300 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 3.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 27..104
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 202..383
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 419..544
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 811..1016
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1528 AA; 174948 MW; DAC1B5B5B03B1990 CRC64;
MASFHHTSIQ TKKSAMAELA FGLSKTVVEA LALKVKDAIS LEVEQWRTVG RELEFIVGEF
EIMQSFFKIA DEERAKSNLV ITWVTQLRNL SYDLEDCIEF VLHLDTKNTW YLRFLPHCAG
KVVLPVDEAV DQVKQLKARV LDMSERNMRY RVINESGSKL DARMQEPSAA SATEFDILFK
ARNAVKEQSG FWDLTGLING KDADLQVISL CGTGGDLGMS SIIKKAYDNP KICKRFKLRA
WVKLMHPFNP HDFIQGLENE FFINSCGTQG EAEGVDFLKM KANEDDSDLL DKFHTKVKEH
KYLIVLEDLS SMVEWHNVRT YLPDMKNGSR IVVSTRQLEI ASLCIGQHYQ VLELRQFSAD
HSVFVFLKED FRLEDMNERN AREVRNWLDT FLHVGCNSEA DKLDSDITLT RNNVKPPMVS
SFCGFAAVKN SNIVKIAYRR HMLKETFDKY AWVNVSCPFN LKDFSWHLLS SLNPESLRNE
DPVEECWKLL HKYHCLVVIV GMQSKECWDM IKANLTSGTY RSCIFVITEK ESVATHCAAS
EDATYNIKDF PIEKGIKSDD MSDGGGPSLK MEELRDWANK FLQVGCHSEE DNPLQKKISE
EDKLDSKITL TRYCSKHHII SSLSEFGATE SDLVKTVYNR HMLMKTFDKY TWVNVSSPFN
QDDFVETLLS DLNSEPLQRP IFVSIPECQY LLREYHCFVV ICDLQSFKKY SQVLEFIKGS
LLTSGPYRSC IVTITGEESA VTHNTGAEDA MSSIEGRTVK TEGFQCDDHA NGRGDPSIWE
TACHWEYNFV LVGRDLELRK LDHQITGTRH SKTSHVVCVL GLPGVGKSAL VRTVFYRVVL
RKTFDKYVWV NVSHPLSITD FCRRVLVHMH SESFKVEEPI EECRKLLHNF HCLVVVDGLR
SKEDWDLING ISVHSSSCIV VITREESVAN HCTPSDAVCN IEGLEHDAAL DLFQTELEKA
GVHQQRDMTK LKHILYKCGG LPEVIVALAR HMADLREDTW EWEWMRLNDN FMHLLQTKSE
LGSIGSLFTW IHSKIRGCPQ PVKKCMFYLS IFPQNSIIRR RRLVRRWIAE GFSEPTDSKS
LEDYMEELFH KLAALGMVQR PPQTNTMAGA KRMSFFQVSG FFREYVISRP REEKVFFPVE
VTVLDEGHRL TTERVGQHIA IGENWERDRI VFDGMNFERL RSLTVFGDWT PFFISEKMRV
LRVLDLENAS GSVTNKDLEV MVALLPRLKF LSLRGCKEIT HLPSSLGTLR QLQTLDIRHT
SVEYLPVSIL RLKRLNYIRA GTMHSAGYNG GVDLPRIEQM TALHTLGVVN VIYHYGLRRL
TQLHKLGVSG ISQKNSRQLL SAISGHNHLE SLSLVLAKDN HVVSWDGINY PKNLRSLKLY
GHVQMLPPQI KELRNLEKLS LEIISFTEED IKVLGKLENL QILRLFVKMF DNGQLQFPIM
GDDFPQLKVL EIDCNSNLHI CFPQRTVRNL EVLKVCYHSG SPLQLSGLDH MISLKKVWLK
GPSDGALLDS VRQQLDRNPK KPVFVPVE
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