ID A0A368QXR2_SETIT Unreviewed; 801 AA.
AC A0A368QXR2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SETIT_4G244000v2 {ECO:0000313|EMBL:RCV22735.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV22735.1};
RN [1] {ECO:0000313|EMBL:RCV22735.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV22735.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV22735.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV22735.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003531; RCV22735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368QXR2; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1182; OS09G0270700 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 21..100
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 179..425
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 801 AA; 91978 MW; 81C1B2DC7F66175D CRC64;
MADALFVVLR KVALSLGERT LERIGAEVVE AAPVLTDFEH SLKQIEDELL ILQAFVGQVG
PHKVGDKAFD AWLDQVRDVA HEVEDIIDEH AYLAAQAVDT GSFFKRKFRQ IKNFVAWQKF
TSQISQVEAR IQRLGEMRNR YGISVGEIHR SNKLRHPNQL FMSESSYLTD NSEIVGHADE
IERLTQWLLE EKQERTLIAI FGMGGLGKST IASSAYKNQK ISRTFDCHAW VTVSQTYQVE
ELLREIINQL IDQRASVAGG FMTMSRLRLV EVIQSYLRDK KYFIVLDDVW DRDAWLFLNY
AFVRNNSGSK VLITTRRMDV SSLAVDKYVI ELKTLPYAES WELFCKRAFY ASKDNICPEN
LRSLAEKIVA KCQGLPLAIV TIGSTLSYRE FEEQEWAFFY NQLSWQLANN PELSWISNVL
NMSLNDLPSY LRICFLYCSL YPEDYRIRRK LISKLWIAEG LVEDREDGTT MEEVAKYYLT
ELTQRCLLRV TECNACGRPR TFVMHDLVRE VTSVIAKKEK FGIAYRDAGI TKVSHEARRL
SIQKANKDLV SQLGNLTLMR SLAIMKVRQS CIAELWSSLT KMPNLSRLLI SACDMDEVLD
LRMLKPLPNL KFLWLSGKLA EGVLPLIFSK FEKLALLKMD WSGLKKDPII SFSHMLNLVD
LRLYGTYGGE QLTFCAEWFP KLNSLQLADM EHLNWIDIED GTMIGLYHLE LIGLRNLKAV
PVGIKYIRKL HQMFLTDMPN EFIQRLQGSD DDIVQHIPNV HIFDSSDSKA VNTFHFVPYL
AKKYGPGATK YAPTYWGSSS I
//
