ID A0A368QZU3_SETIT Unreviewed; 1374 AA.
AC A0A368QZU3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=SETIT_5G008400v2 {ECO:0000313|EMBL:RCV23467.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV23467.1};
RN [1] {ECO:0000313|EMBL:RCV23467.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV23467.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV23467.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV23467.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM003532; RCV23467.1; -; Genomic_DNA.
DR RefSeq; XP_004971473.1; XM_004971416.1.
DR STRING; 4555.A0A368QZU3; -.
DR UniPathway; UPA00143; -.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR47446; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR47446:SF2; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00504; Ubox; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 416..491
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 1129..1165
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1340..1374
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 225..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1374 AA; 148575 MW; 7EAC5F2480F1E3E3 CRC64;
MAGPTPTYSA IIAHTAAFLA ELVADPLLRR HLLSAAAASD GGGGQQRRQH PAATLQALSL
VSDALDTAAS ASPSPSSLRA AERLLQSLPA ATPLSCLLLA LASAARRRGG GAAADAVLDL
FALDPALARN ELAPAAFEAL FAPRLLPVMR HFAARRASAA AGNGDEDSRS DEATALSAMR
VLSLMSGAQA QEMRALEREY EMVLDVNCRA YALYLKKILD AGETSLMSSS PQPPPPELVF
GVGADEEDHG GDDDDAPEND ESASSQSGFR YNPMWAETEE PGDLYPRRQG GGRGRRDLMR
PPSLYPQRVP PHLIVQQQQQ QSPPVGRGSP ASRLRADNSR LQSPAAPSDD SVEDSSSELG
AGKEEKRPAS PPSLSKPRRA PPRPGADDAR LSPDPARSPV RGDGDPQPPE TPQPAATPKD
FVCPITSQLF EDPVTLETGQ TYERRAIQEW LDRGNATCPI TRHRLHGAQL PSTNYVLKRL
IAAWRDDQNQ PQLKTMDSPA PTPTPPFKAI SSPSPDTSAS QASAASPTSV IAQATLETAA
GELRAAVACL CTSEDLAESE ESVLRIERLW REAGTEHAVL AALARPAVIN GFVEILFNSV
SARVLQAAVF LLAELASRDD AVVQTLTRVD SDVDCLVALF KKGLVEAVAL ICLLSPTPEQ
LVEMDMAEAL VSTIRRGDDE DPPLRMCIKP KAASVILLSQ ILAEAGTDRD SSTLPVPRSA
LLSERFVRSV AVSLEAEQVE ERLAAMRILL RCIWEDGHCR STIADKASLG AVLDAFHAVG
DADKFDIVRF LYELLKLKKR SAAERVLRTI KDGGSFSRMH TLLVHLQSAP PEHSPVVAGL
LLQLDLLVEP RKISMYREEA VDCLIQCLKN SDFPRSQLLA AETIMCLPGK FSSSGRPLTR
STLLKLARVK ERHRQSQDLS IVRADAGEDE MEEEKAASEW ERKTAYALVS HEFGLVFEAL
SECLRSKNAE LFTTSLVCAT WLVYMLSLLP DTGVLGAARV CMLRQFVIVL RSAKHGSDRV
LAMVAVRSFM NDREGMHDIT TYIKDVLKTL RELKKSSGLA FEMLKLLSDG QESSVDMWNH
KEINQADCSS NGEVTSIVYL KNHIFSGHSD GTLKVWEGSE NILRLVHEAQ EHTKAITSLS
VLHSEEKLYS GSLDRTIRVW QLRDGVLQCV ETHDTKDPVQ NLAVASAMAC FVPQGAGVKL
LNWNGNSKLL NANKYVRSMA LVHGKLFCGC NDSSIQEIDL ASGTLGVIQS GNKRILGKAN
PIYSLQVHDG LLYTGSTPSM DGASVKVWNC GNYNLVGSMP SSMEARSLVV SADLIYVGSR
NGAVEIWSRE KLTRIGTLQA GGPSCRVQCM AVDGDGDVLV VGTSDGRIQA WGLT
//
