ID   A0A368RTE9_SETIT        Unreviewed;       959 AA.
AC   A0A368RTE9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Ribonuclease {ECO:0000256|PIRNR:PIRNR017179};
GN   ORFNames=SETIT_7G083600v2 {ECO:0000313|EMBL:RCV33439.1};
OS   Setaria italica (Foxtail millet) (Panicum italicum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX   NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV33439.1};
RN   [1] {ECO:0000313|EMBL:RCV33439.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yugu1 {ECO:0000313|EMBL:RCV33439.1};
RX   PubMed=22580951; DOI=10.1038/nbt.2196;
RA   Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA   Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA   Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA   Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA   Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA   Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT   "Reference genome sequence of the model plant Setaria.";
RL   Nat. Biotechnol. 30:555-561(2012).
RN   [2] {ECO:0000313|EMBL:RCV33439.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Yugu1 {ECO:0000313|EMBL:RCV33439.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cytoprotective ribonuclease (RNase) required for resistance
CC       to abiotic stresses, acting as a positive regulator of mRNA decapping
CC       during stress. {ECO:0000256|PIRNR:PIRNR017179}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
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DR   EMBL; CM003534; RCV33439.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A368RTE9; -.
DR   STRING; 4555.A0A368RTE9; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.40.50.90; -; 5.
DR   InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   InterPro; IPR002999; Tudor.
DR   PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR   PANTHER; PTHR12302:SF10; RIBONUCLEASE; 1.
DR   Pfam; PF00565; SNase; 5.
DR   Pfam; PF00567; TUDOR; 1.
DR   PIRSF; PIRSF017179; RISC-Tudor-SN; 3.
DR   SMART; SM00318; SNc; 4.
DR   SMART; SM00333; TUDOR; 1.
DR   SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS50830; TNASE_3; 3.
DR   PROSITE; PS50304; TUDOR; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          5..145
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          274..443
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          466..592
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          709..771
FT                   /note="Tudor"
FT                   /evidence="ECO:0000259|PROSITE:PS50304"
FT   REGION          939..959
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   959 AA;  106419 MW;  6F8DE18A1448D435 CRC64;
     MAASGWLRGK VKAVPSGDTL VIISIAKADT IPLEKSITLS CIIAPRLARR HGTDEPFAWE
     SREFLRKLCI GQEVKFKVDY VLPGSSREFG TVYLGGDTNI AGLVVAQGFA KVKEQGHKGY
     VNLYVTDLLR LEEIAKDQGL GRWSKEHGAA EASVRILPTS TMGEAAPSDV KGFISEMKGK
     ALEAIVEQVR DGSTIRVCLI PSFHFFSDRF GKEAKHFTET KVLSREVRVI LEGTDSFDNM
     FASVYYSDGN TAKDLALELV ENPPVTNTAP IHNQKFTGKV IEVVNGYCIV IADDMVPVGS
     PLAERRVNIS SIRPPKLVDS SGESKTIEHF ARAAKEFLRT RLIGKQVHVS MEYSRRINIS
     NGHAADKTNI VDTRVLNYGS VFLPSQSGSS GNLFGANVAE LLLSRGFADI TRHRDYEERS
     QHYDALLAAY SRAEKAKKGY HAKKYYPATH MNDLTTIFFH LLQRNKRHSA VVEYIFSGHR
     FKLTIPNETS TITFSFSCVR CPGKNEPYSD GAIALMRRTI LQHDVEIEIE AVDRTGTFLG
     SLWESKNNMA YVLLEAGLAK LSSFGLDRIS DAQTLIRAEK SAQQKKLKVW ENYNEAKVIP
     HGSLMGQNGK ESFKLASMKF NDIPETLMVT KDFPDTLSNT LEVQDQPRHC PSNTSEVQAE
     PKNHVVPLPS RWSSLFKDKV DILKDEVPLD TSKAEDLSSN GPSDAVPFNP TKGDVVLAQF
     TLDNSWNRAM IVSEHQGPME REFLVFYIDY GNQEIVTYSR LRPAHANQST SLIPPLAKLF
     LLAFIAVPNL KDNLGEQAAR YLSMVLLDNE KEFKATIEER ATVESKQEGQ GTGEVLVVTL
     FDEDAESSIN AAMLENGLAQ IETHRLISRE RRAAVKNLEE FQEHAKKERC GIWHLEGVGV
     PDKSAKDGNA CDINDDEDLL APARAQPPSR GFDLIDLIAS KSTGTPKPSR EHVMGDSLP
//