ID A0A368RVF7_SETIT Unreviewed; 726 AA.
AC A0A368RVF7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=SETIT_7G138400v2 {ECO:0000313|EMBL:RCV34131.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV34131.1};
RN [1] {ECO:0000313|EMBL:RCV34131.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV34131.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV34131.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV34131.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; CM003534; RCV34131.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368RVF7; -.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016871; F:cycloartenol synthase activity; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 3.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 98..358
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 487..717
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 726 AA; 82567 MW; 7ADDB9A6B0E22B16 CRC64;
MWRLKVAEGG GPWLWSTNNF AGRQVWEFDP DHGTAEERAQ VEEARRGFAD HRFELRDSAD
HLMRLQFAKA NPLKLDLSAT KLEEEEDVTE EAVSTSLRRA ISRLSTLQAH DGHWPGDYGG
PMFLIPGLII TLYVTEAMSA VLSSEHQKEI RRYLYNHQNE DGGWGLHIEG PSTMFGSVLN
YVSLRLLGES PSGGDGAMEK GRNWILGHGG ATLTTSWGKF WLSVLGVFHW SGNNPVPPEV
WLLPYCLPFH PGRLWSHCRL VHLPMSYIYG KRFVGPITQV VLDLRKELFR DAYDEINWDK
VRNQCAKEDL YCPHSFVQDI LWAALHKFVE PVMLDWPGSK LRKKALDIVM QHIHYEDENT
RYICIGSVNK VLNMLACWIE DPNSEAFKLH IPRVYDYLWL AEDGMKMQGY NGSQLWDTAF
TVQAILAADL IEEFGPTLKL AHDYIKNSQF LDDCPGDLNY WYRHISRGGW PFSTVDQGWP
ASDCTAEGLK NDDGGFATYE LTRSYAWLEL INPSETFEDI MIDYPHVECT SSAIQALASF
RKLYPGHHRK KVDNCIIKAA NFIESAQRSD GSWYGSWAVC FTYGTWFGVK GLTAAGWTFR
NSPAIRKACD FLLSKQLPCG GWGESYLSSQ NQVYTDLEGR RPHLVNTSWA LLALIDAGQA
ERDPVPLHRA AKVLINLQSE DGGFPQQEIS GVFNRNCMIS YSQFRTIFPV WALGEYRCRV
LAKAKH
//
