ID A0A368S5W1_SETIT Unreviewed; 1161 AA.
AC A0A368S5W1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=SETIT_8G088800v2 {ECO:0000313|EMBL:RCV37761.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV37761.1};
RN [1] {ECO:0000313|EMBL:RCV37761.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV37761.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV37761.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV37761.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003535; RCV37761.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368S5W1; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45707; C2 CALCIUM/LIPID-BINDING PLANT PHOSPHORIBOSYLTRANSFERASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR45707:SF84; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 22..308
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 50
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1161 AA; 133242 MW; FA3E7E222D8A6677 CRC64;
MKGWTDDHPR KLQYSLVKEI TNNFADELGR GTFGRVFKGL LDDGEEVAVK LLRYFTPEIS
DQQFQNEFGN LKKLKHPNIV QLLGFCDEPE EEIIEHKGKL ILCYRIRRAL CLEYVPNGSL
RKFLSGGCLS KNWPIRYKII KGICEGLQYL HKIPIFHLDL KPDNILLDEK MLPKITDFGL
SRLIGEGNTK RTMTPLGTLG YLPPEFINNQ IISREYDIYS LGVIIMQIIT GVTGFSDFAD
MEPQEFIEHV HDNWKRSLEE IPEYASLEAD CKQVKGCMEI AINCKKKKRH ERPTIEDIIS
KLDETETVKI DTQLSIKKGY FEESRFLSSG ILGRPCQLQS AGAVLLAVTK IGSILGDETS
KAVINKLSWK VHSLKELPWK VDQIRMNLTF MSQIIQQIGT VYLTDELANN WIGEVRKVAY
RVEDVVDKYS YHVFQLTQEG FLKFFIKGTH NDIVFSAITD EIAHIEEEIN QVIHMKDKWL
HQTQLVSNNQ QLAEIERQRS QDGFPDFVKD EDLVGIEKNR KLLSGWLYSD ELDSTVITVS
GMGGLGKSTL VTNLYEREKV NFPVHAWIVV SQICPADALL RKLLWKIGNK RAAEIKKKLQ
NRKCLIVLDD VWEQEVYFKI HDAFQNHQAS QPLDGPDAFD LFCRRAFHNN KDHKCPKEFE
EIATSIVDRC HGLPLAIVTI GSLLSYLEYI IWNQTYNQLR SELSTNDHVR AILNLSYHDL
SEDLRNCFLY CSLFPEDYPM SRESLFPEDY PMSRESLVRL WVAEGFVLSR EKNTPEEVAE
VNLMELIHRN MLEVFGSAND YEAIIQVDPH VRRLSLCRWK VNTSLKHLTV LELQDSNITE
VPTSIGNLFN LRYIGLRRTD VKSLPESIEN LLNLHTLDIK QTQIEKLPRG TVNVKKLRDL
LADRFADEMQ SDFRFFIGVE SPEGLSNLEE LRTLETVQVS KDLAEQLKKL MQLRSVWIDN
VSASDCANLF ATLSTMPLLS SLLISARDVN ETLCLQALDP ISTKLHRLIV RGQWASGTLK
YPIFRNHGEH LKYLALSWCQ LGEDPLGVLA PHVPNLTYLS LNRVNSASTL VLSAGCFPHL
KTLVLKRMPD VKQMEIGDGA LPRIEGLYIV SLAQLDKVPQ GIELLLSLKR LWLLYLHDEF
KTLWQTSGMH QKMQHVPEIR I
//
