ID A0A368S9B0_SETIT Unreviewed; 1191 AA.
AC A0A368S9B0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=SETIT_8G186400v2 {ECO:0000313|EMBL:RCV38988.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV38988.1};
RN [1] {ECO:0000313|EMBL:RCV38988.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV38988.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV38988.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV38988.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003535; RCV38988.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368S9B0; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1135; OS08G0246300 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 1..70
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 211..383
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 395..627
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RCV38988.1"
SQ SEQUENCE 1191 AA; 135978 MW; 84B4D2177F052933 CRC64;
LEEEEKLEKS VQRDLLAISD EFEMMYSFLK DVKDRVTDNV TRTLVRQVRN MALDVEDCIE
IIVHLDHKPH WWRRMMLPWC MPAAPPGKDL DAAVANIEQL KARVEAMGQR NLRYNRIGDS
GHKPAEQTHQ QAVANAMQPN ILGSATNVAK QSGQVDLVML ISGKNTNESR QRKGGAEGDQ
AHHLLGDKDD DDCYYDCDEE FKVEKEADDV HQLKVLSVVG TGSDLETMSM KKAYDDIETR
KSFNCRAWVK LVHPLHPIEF IRSLLAQFQN NACPEQDKTV KVLDVMVATD GVLIEEFKKK
ISQKYLVVLE DLSTMVDWEA LRVYLLDNKN GSCIVVHTRH LGIACSCVGH GYRISELEKL
SADHSVRVVY KEDVAKKVEG STVNKEQTAR ECWLHWLTAG PEGGVVSVWG MTGVGKSFLI
QHFYRRMKES RSTDSCKFGW VNVSRPFDLR VLSRNLLSEI NPDSQDHQVM STIKDPIQGC
REYLQREENS PYFIVIDGLR SKDEWDLIRA CLVLSRNLDF RFETSSGEEN KNVVIIITNE
ESVANYCATD HKKMWKVKGK KVWNVKGLEV SEAIKLFDQL VATNKRWWFW ENKNLETKHR
NDEARHILLQ KCGGLPKVIC AVAETSNMVR DIKLQDNLVS KLEATRSLED VLSWLLSYFQ
SCQDSLKPCI FYLSIFPVNH TIRRRRLIRR WIAEGYFRDN KESTAEENGE RSFSNLVDLS
MIQKPRTSVD DTRMPLCQVN GFLREYIVSR LMEENLVFEL EGHCRKNIQR TGRHLAIDNS
WDRDRNVFES IDLSLLRSLT VFGKWETFII SDRMRLLRVL DLEDVSSGVT NVPLLRGCRE
ISHLPDSLGD LKQLQTLDIR ETSVSKLPKS IIELEKLQYI RAGTNKHLQA CEAAENPSAA
EAAAQMGRPC ATLGSKLTIH RRHGSHSGIK VPRGIGKLSS LHTLGVVNIH ASDEDSILEE
LKNLTQLHKL GVSGINRKNS EKFFSDISRL VHLESLSLKM QANQDNEAAG LMADISSPLE
KLRSLKLYGL VDRLPSWIMQ MCLQLPRLEK VDLQMKTLPQ QELDFILTLR YLRSLRLRLA
EFQGGELRFG WSIAQRPGTW IIYFLEIACN SRLQAVKFGS RVDVVILKIR CCGVSSSLLF
SGLQSLESLK EVWLSGSYDQ TFNKHLEKEL KENENKPILK LEEPSSSPDG C
//
