ID A0A368SAA1_SETIT Unreviewed; 1236 AA.
AC A0A368SAA1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RCV38750.1};
GN ORFNames=SETIT_8G167300v2 {ECO:0000313|EMBL:RCV38750.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV38750.1};
RN [1] {ECO:0000313|EMBL:RCV38750.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV38750.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV38750.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV38750.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM003535; RCV38750.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A368SAA1; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1114; OS02G0475500 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 13..95
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 179..345
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 407..683
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1236 AA; 139223 MW; FA32162457A38F54 CRC64;
MEATALSVGK SVLNGALGYA KSAIAEEVAL QLGIQRDHAF VSDELEMMQS FLMEAHEERD
DNKVVKTWVK QVRDTAYDVE DSLQDFAVRL ERPSWWRFPR TLLERHRVAK KMKELRAKVE
DVSQRNVRYR LIKGSGSKAT AATEQSSIIA AAIFGVDDAR RAAKEESQRV DLVQLINKEG
DDLRVIAVWG TGGDIGQTSI IRAAYKNPDT QSKFPSRAWV RVTHPFSSKG FVQSLVNQFL
AVEGFKDILD TEKTAHNLVQ EFDGYVKEKR FLIVLTDLCT IEEWDQIEKC LPNNNKGSRI
IVSTTQVEVA SLCAGQDSQA SELKQLSADH TLYAFYDKGS QNKIVSMDPV SNSDVATTST
NAQTMAPSEI AENQCKDVDE MKVHKKSLTR IRTGVGSLEE SQLIGREKEI SKIIGLISNK
ASQVISVWGM GGLGKTTLAN GIYQSLKLSD MFEKHAFVTI IRPFNHADLL RILIGRLQEE
SSKKEELLNN RPSKTKSLAM MGVEALTKEL KRLLEKKSCL IVLDDLSSIE EWDHIRQGFS
WMKKTTRIIV TTREESIAKH CSGKYGIVHN LEVLKEEDAL NLFSLKNPEF VEEANQNLKK
YGGLPLVKAT DLIKKNPELF EETKKILKKC GGLPLAIVTI GGYLASRPKT RAEWRKLNEN
ISAELEMNPE LGMIRTVLQT SYDGLPYELK SCFLYLSIFP EDYIISQRRL VYRWTAEGYS
QERRGKSANE IAENYFTELK YRSMILPFQQ SVHSRKSIDS CKVHDLIHDI AISKSMEENL
GFRLEEGCDL STHGAIRHLA ISSNWKGDQS ELERIVDLSR LRSLTVFGEF RPFYISDKMR
LLRVLDLEDV KGLKYYHLDH VWKLLHLKYL SLRGCTGIVL LPNSLGNLRQ LQVLDVKDTS
VMALPKTIIK LRKLQYIHAR WGAGYVPKEK DSLTRRCLWG AGQCATCCVP LLRDIDGPLH
KALTRRDACT FACCVLYPAV MMGANEEGGV MVPRGTRKLK ELHTLREVNV GRGNAVLQDI
KMLTGLRKLG VAGINRKNGP AFRAAISNLS RLESLSVSSA GKPGLHGCLD DISPPPENLQ
YLELYGNLET LPEWIKELPH LVKLKLVSTR LLEHDAAMEF LGKLSKLKIL SLSWESFQGE
ELRFRSEQTG RAFGSLSVLM LANIGYIKSV KFEEGIMPKL ELLQIIGEAN NEIGFSGLEF
LQSINEVQLS NNNGWLKKKI QELLAGNRNE PIVTVY
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