ID A0A369AFR0_9FIRM Unreviewed; 3372 AA.
AC A0A369AFR0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=RHS repeat-associated protein {ECO:0000313|EMBL:RCX08180.1};
GN ORFNames=DFR58_1448 {ECO:0000313|EMBL:RCX08180.1};
OS Anaerobacterium chartisolvens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Anaerobacterium.
OX NCBI_TaxID=1297424 {ECO:0000313|EMBL:RCX08180.1, ECO:0000313|Proteomes:UP000253034};
RN [1] {ECO:0000313|EMBL:RCX08180.1, ECO:0000313|Proteomes:UP000253034}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27016 {ECO:0000313|EMBL:RCX08180.1,
RC ECO:0000313|Proteomes:UP000253034};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCX08180.1}.
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DR EMBL; QPJT01000044; RCX08180.1; -; Genomic_DNA.
DR OrthoDB; 9771173at2; -.
DR Proteomes; UP000253034; Unassembled WGS sequence.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07473; Peptidases_S8_Subtilisin_like; 1.
DR CDD; cd06583; PGRP; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 3.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR Gene3D; 3.40.80.10; Peptidoglycan recognition protein-like; 1.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 7.
DR InterPro; IPR036505; Amidase/PGRP_sf.
DR InterPro; IPR002502; Amidase_domain.
DR InterPro; IPR045351; DUF6531.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034204; PfSUB1-like_cat_dom.
DR InterPro; IPR006619; PGRP_domain_met/bac.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 4.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF01510; Amidase_2; 1.
DR Pfam; PF20148; DUF6531; 1.
DR Pfam; PF01344; Kelch_1; 12.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF05593; RHS_repeat; 7.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00644; Ami_2; 1.
DR SMART; SM00612; Kelch; 12.
DR SMART; SM00701; PGRP; 1.
DR SUPFAM; SSF117281; Kelch motif; 3.
DR SUPFAM; SSF55846; N-acetylmuramoyl-L-alanine amidase-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000253034};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..3372
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016811228"
FT DOMAIN 3187..3326
FT /note="Peptidoglycan recognition protein family"
FT /evidence="ECO:0000259|SMART:SM00701"
FT DOMAIN 3206..3355
FT /note="N-acetylmuramoyl-L-alanine amidase"
FT /evidence="ECO:0000259|SMART:SM00644"
FT REGION 3064..3088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3109..3136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3152..3194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 195
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 255
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 411
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 3372 AA; 373300 MW; 0DF9449B2911AF4D CRC64;
MKIKSFLNKA ILITLIACLF FVPRYIQAAD GTMLKAGVGK NGGISYSERK TDRFIIKYKN
EKNRATEARN TKNGIMAANM PELKNYDVVT TKTRMKSSEL LAEIENKSTY GIEYIQPDFE
MTISSEDPQY TNQWGMYSKY SAIPDVNTLP DDEKIRQFIL EDAKSMGLPS IRIDANVPAA
WEKADGSGVM VAVLDTGIDI THEDISGNIS VNVAEIPGNG IDDDGNGYID DVSGWNFCDN
NNTVHSKETE CDEWHGSHVA GIIAASKDNG KGIAGVAPAA KVLPLKVFKG GRAYTSDIIA
AIQYAGKMGA KVVNCSWGST EYNQALKDAI EHSDMLFVCA AGNSHTDIDN NPVYPAAFDC
KNIITAASID KNGVLSGFSN YGKASVDIAA PGNEIISTLP GNAYGKSSGS SMAAAFVSGE
AALLSDMLKG ISIADLKNRI INSSDRLSSL TDKLGGGGKL NCGNAVSGIN KDEIVQIAFS
DNDPCDSSSQ PEQGYELLAT DSWAGKASMP TARHNFGSAE TGGFIYAIGG NKSTYLNTVE
EYDPVLNNWK TKAAMPTVRE CLSVVAAYGK IYAIGGYNGN YLNTVEEYDP ASDKWIAKAG
MNTARQSAGA CVVNGKIYVI GGYNGNYLNT VEEYNPLTNS WRTLASMSAP RSQLGVAAVN
GKVYAVGGYY LNQYLNTVQE YDPSTNVWAG KRAMPTARGS FGVSVVNSKI YAVGGICGSG
CLNNAEEYNP ALDTWIAKTP MQIGKCNIST TSVNGRIYIM GGYNAGSLSS TEEYTPASDV
WVTKAPMPTA RGFAGVAAID GRIYVAGGTY EGSSALEYKA INTFEEYDTE KNTWSVKPSM
PTPRFGVGGA SAYGEFYAIG GWNWDINGNL DINSISKDTV EAYNPATGRW VSKASMGSQR
FAPGVVELDG KIYAIGGAGQ KSAEVYNPLT NRWTPIADMS EARYGLAVAA VNGKIYVMGG
YDYIFDKNLS DTVEEYNPST NTWTKKASMP TKRNYMGAVA VNGKIYIIGG NSGKYINNVD
IYDPATDRWT TGTGMSVGRM RLGTVMVNGR IYAIGGYNGS YLSTVEEYSA EYDRYIMQTH
FGEDGTNPAS GNFSRSYTDM SMDVPGFKLN IGRTYNSRND KSGPLGKGWT FSFEGNIKDD
PNDSTLKVVT LPDGSVQTFK KSKDAGSNDI FTAKDSRSRL ELKAGGSYVL TTKDQYSYTF
INGWLTLMQD KFGNTVSISV DSNGKISKIT DIAERSITVD YSGTSFIRFV KDVSGGRTVE
YQYENNQLVR AIDPAGNITR YSYDSSGYMN GVKDHNSNRI EDLVYNHSAG DNQHKVSRIT
DAYGNIFKYA YDNANKEASI TDSNGRQTVQ HYDSYMYTSS SRDAEGKEEI TEYNLDINGG
NRFGEERAVT DRNGNKTAYD RDGRGNITKI TNPDGSTIEY TYDAKNNVIS EKNEQNKYTF
YIYDAGMVYL LKKIEPLNGT DLYYQGCDES KFAITGYTYY TSQECQSNGY KAKGLLKENK
SPEGKITAYT YYSNGCLKTE KDAQGKTTVH NYNSIGWETS TISPMKFKTE YFYDNNGRLE
KTVANDGDGS AKPITTSSVT RTTYNIMGRK TQEVSPNLYD PAKDSLTSHT YTGNHGYRYV
YNADYTLKRV TDPENNVTEY LTYDMYGNVL KEKKPNGAVY EYAYDALNRI KKVYFRENAS
ASSTLLEEYS YDIVNGTTLQ NGAILKNTRK TRTVYLNDKE AAVTKYIYDY AGRLINQQNA
DGTSSSIEYY LDGRVKSTTD ESLNKTYYKY GTYDSANNFR YDEKWALIEK SGSDALYTYS
AVVYDKTGRI KSEKTGKQKV SLWNAPSDFV TKTYEYYGND KVYSITFNDG RKTQYQYDDD
GNVSREEVYT DSTNKRTTLY ENNQFGLPCK KKVYVKLGDI YDCDFSSTFE ILPTTELAYD
KNGNLKSVKT PEFVTTIYEY DNMDRRTSTS QSGYDEYMNA AVISASTLYN WEGKPIEATD
TKGNKTFYHY NARGFLEKVE ETAAVNGADA RLYTLYGYDN AGRKIYEVSP KNYFPGQSVQ
SMDRTEYTYD LMGRIKTQNE VFREKTVDPG DNSKWITSWV TITSKAYKYD SMGNIVKELD
SLGYEAGTGT TADQKINTGY GTVYTYNCQG KVQTVLDPVS KDRGLAYSTK YEYDGMGRKV
YEISAKGSGS GTYYSSTGYE YDDAGNVTEV RTKKNINDTG SSGQLVQVYT YDLMGNLLTR
KDGNSNVTTF EYNAMGKLRK VIYPGDASIP SDIVIYQYDL VGNLKKQQNS LDTVDLYTYD
NQGRVLSHTQ KKKDSSQTIT TSIRYDKNGN KRFETDGNGV KRENTYDQAD RLISTKITVT
GERNRKTQKV TSYEYDANGN ATVTTDWRGN RYTSEYDPIN RLIEKSGPYG VIQKLEYNHN
SSQKISYDAL YNITAFEYDK DNRLINTIDP EGHISLQSYD NAGNIGTRTD GRGNKTTYAY
DEFNRLEKVT DATGQETSYS YDLNGNMLTQ TDAKGNTIAF EYNVRNKAVK RIDAGGRTGE
PGSYTYDSAK VEKYTYYADG SLYTKEDRNG KMTAYEYDCH GRMLSQSVNG EAITYTYDRN
GNQLEITDSA GKTTRTYDEQ GRVRTKAVPN IGTIEFRYDI IADMDPGCWA ETSIDPKGNT
ITKIYDSEGR LWKVASEGKE TIYSYYGNGS KKGVEYSSGA REEYTYYKDG MLAALKNYVM
QNGSEKLIDS YAYEYDAARN QISKDEYING SAKGTTVYEY DSLNRLKSVT EPGSSRTTVY
TYDAAGNRQT EKVTENDGTV STQYNYNPQN RLDSTVTGYG GGIEETVRYS YDNNGNMTYK
GVETTKPYDE TGEEKIEVYA GEEDKTDTDI AFYMYDDWNQ LVEISAGGQT SKYLYNGEGL
RVGKEIGGKT TRYLYEYDNI ILEVDGEGNQ TGRNVYGTNL LMREVEGETL FYLYNGHGDV
TSLVDTAGRA KVSYYYDAFG NILEQSGSAS NSITYAGYQY DDETGLYYLR SRMYDPVTAR
FMQEDTYMGQ ASDPLSLNLY TYCHNEPIMY VDPTGHKEEL DKMIKSSATK TAIDKATKAY
EQAKAKNDKA GMAKAHDDAQ KARSEYAKTS KDAHYIEAKY GTSALASYLG SGSSGKSSTQ
GTGKDSSPAP NKGNDALKQQ IKTGMDKQLN NIASTQGTGK SGTSQGTGKS GTSQGTGNPK
LGFDSLSNYK TRDQWGANPV NEKVGVERIK NPNQYFDSVV IHHTERATDE EIKHLQKYFQ
DDRKYPDIGY HYIIGGGGTI YEGMPINLKG WHVEKNNTGK IGVVLTGNFN DGSGISGNVK
DAINWLKGEG HTEPSKEQIE SLKQLIKVLD SQYGIDKVGG HKDFALSTSP SECPGNIAYP
ILEKEGIIKL GK
//
