ID   A0A369GXQ2_9HYPO        Unreviewed;      1351 AA.
AC   A0A369GXQ2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CP532_5846 {ECO:0000313|EMBL:RDA88554.1};
OS   Ophiocordyceps camponoti-leonardi (nom. inval.).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=2039875 {ECO:0000313|EMBL:RDA88554.1, ECO:0000313|Proteomes:UP000252748};
RN   [1] {ECO:0000313|EMBL:RDA88554.1, ECO:0000313|Proteomes:UP000252748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC 80369 {ECO:0000313|EMBL:RDA88554.1,
RC   ECO:0000313|Proteomes:UP000252748};
RA   Kobmoo N., Wichadakul D., Arnamnart N., Rodriguez De La Vega R.C.,
RA   Luangsa-Ard J.-J., Giraud T.;
RT   "A genome scan of diversifying selection in the zombie-ant fungus
RT   Ophiocordyceps unilateralis complex supports a role of enterotoxins in
RT   coevolution and host-specificity.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDA88554.1}.
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DR   EMBL; PDHP01000007; RDA88554.1; -; Genomic_DNA.
DR   STRING; 2039875.A0A369GXQ2; -.
DR   Proteomes; UP000252748; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000252748}.
FT   DOMAIN          12..237
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          256..559
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          573..748
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          767..1318
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          154..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1317..1351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1325..1341
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1351 AA;  146486 MW;  CD7E2FEB543BE4E0 CRC64;
     MTPAAAMTPG IRIAIDRGGT FTDCIGEQDG QETVVKLLSE DPSNYPDAPL EGIRRILSHF
     LRRPIPRGQA LDTSPIHSIR MGTTVATNAL LERKGEPVAL VVTSGFRDCL AIGNQSRPRI
     FDLAINKPDV LYQVVVEIDE RVTLEDYAED PNRVVTTVPE PPDGGDGGGG GGDASTLVRG
     LSGEVVRILR RVDDDEIRSK LKPVYEAGIR SVAVCLMHGY TFPHHEARIG AIAREMGFVH
     VSLSHELMPM VKLVPRATSV CADAYLTPAI RRYIDGFQRG FDGGLGVRRL ESAGPAARCE
     FMQSDGGLVD IDGFTGLKAI LSGPAGGVVG YALTSYDPDT KTPVIGFDMG GTSTDVSRYG
     DGRYEHVFET TTAGVTIQSP QLDINTVAAG GGSRLFFRNG LFAVGPESAA AHPGPACYRK
     GGPATVTDAN LCLGRLLPDF FPRIFGENED QGLDPDASRK VLQDLTDQVN RETGKGLTVD
     EVAHGFLTVA NEAMTRPIRS ITEAKGHDTS KHRLATFGGA GGQHAVAIAR SLGIRQILVH
     RHSSVLSAYG MALADVVDER QEPDASVWGA GQDVVQALRR KMDRLRNKSR EALGGQGFHD
     DDMAFEEYLN MRYRGTESAL MIVKPEDWDF GKAFVDHHRF EFGFTLDDRD VIVDDVRVRG
     IGKTRRRREP TVDEQLKTVK RQAVAEEKRH GTHRVYFDGS RLETPVYRLD KLDVGDEIRG
     PAMLADGTQT IVVTPQTTAL VIQTHVILDV GQDGSSRSDE PSDDGLDPIM LSIFGHRFMA
     IAEQMGRALQ KTSVSTNVKE RLDFSCAIFD SSGSLVANAP HLPVHLGSMS TCVRRQAEIW
     EGRLHRGDVI ITNHPSYGGT HLPDVTLVMP AFDASGERIL FFAASRAHHA DIGGITAGSM
     PPHSRELFQE GAAITSEKLV SGGRFDEARV VELLYDEPAK GAGCSGTRCL DDNINDLRAQ
     VSANQKGISL IEGLVSEYGE EMVRRYMAGI QDNAERCVRR LLRDVHARFS GAELSAEDHM
     DDGSPIRLRV CIDPDEGSAE FDFAGTGPEV YGNTNAPRAI TYSAIIYCLR CLVSEDIPLN
     QGCLKPIAVR IPDGSMLSPS PGAAVVGGNV LTSQRITDVI LKAFRACAAS QGCCNNLTFG
     FGGNRKGEEA VRGFGYYETI AGGSGAGPDW EGSSGVHVHM TNTRITDAEV LERRYPVVLR
     EFSIRRGSGG AGQHRGGDGV VRDLEFRIPL QVSILSERRV YRPYGLEGGE DGACGLNVWV
     RRVEKTNWSR SLTRLRNGED DGDKEFEERR INLGAKNSAA MQAGDRIIIC TPGGGGWGVQ
     GRPGKAKQRL DHTEGWRKGS AAAREETALQ A
//