ID A0A369HB14_9HYPO Unreviewed; 408 AA.
AC A0A369HB14;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CP533_4516 {ECO:0000313|EMBL:RDA93879.1};
OS Ophiocordyceps camponoti-saundersi (nom. inval.).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=2039874 {ECO:0000313|EMBL:RDA93879.1, ECO:0000313|Proteomes:UP000253071};
RN [1] {ECO:0000313|EMBL:RDA93879.1, ECO:0000313|Proteomes:UP000253071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC 79314 {ECO:0000313|EMBL:RDA93879.1,
RC ECO:0000313|Proteomes:UP000253071};
RA Kobmoo N., Wichadakul D., Arnamnart N., Rodriguez De La Vega R.C.,
RA Luangsa-Ard J.-J., Giraud T.;
RT "A genome scan of diversifying selection in the zombie-ant fungus
RT Ophiocordyceps unilateralis complex supports a role of enterotoxins in
RT coevolution and host-specificity.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDA93879.1}.
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DR EMBL; PDHQ01000020; RDA93879.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369HB14; -.
DR STRING; 2039874.A0A369HB14; -.
DR Proteomes; UP000253071; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14232; GAT_LSB5; 1.
DR CDD; cd16980; VHS_Lsb5; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR044103; GAT_LSB5.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR045007; LSB5.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR PANTHER; PTHR47789:SF1; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000253071};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 18..146
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 210..298
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 149..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..367
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 46007 MW; A91452EAB9C6D3B3 CRC64;
MFSQKKPYSA ITVNIENLTS GSYSVDDFSG IPDLVEVIKL QATGPTEAAR AIRKKLKYGN
VHRQLRALVI LDGLIQNAGS NFQRTFADEP LLERLRVCGT SGLSDPAVRK KATELFREWS
QYASTPGLER VARLYRELPK RKVTVTQDKS KVIRETDNPF GDDEEREADE APKAGPSAST
QPLDYDKKKK KKKEKHHRFG SSRKSFSLEA EKETMKSIIA EASIESTNLM NSLQSINRER
QRISENRVTV QHFEACKQLR RRILRYIHLV DSEQWLGSLL HANDELVHAL MSFEQLDRSV
DADSDSDDEL AEQAHLYRMN TGSHKSSSSH GGHAAPSHRA LDLEGLTLNP PAKPAPPPIP
RPPDSTAGPR RPRVEQLKLS EQEDDDDDPF SDNNVVGTPP FEREQPRW
//
