ID   A0A369HFM2_9HYPO        Unreviewed;       785 AA.
AC   A0A369HFM2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Alpha-N-acetylglucosaminidase {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=CP533_5286 {ECO:0000313|EMBL:RDA94032.1};
OS   Ophiocordyceps camponoti-saundersi (nom. inval.).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=2039874 {ECO:0000313|EMBL:RDA94032.1, ECO:0000313|Proteomes:UP000253071};
RN   [1] {ECO:0000313|EMBL:RDA94032.1, ECO:0000313|Proteomes:UP000253071}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC 79314 {ECO:0000313|EMBL:RDA94032.1,
RC   ECO:0000313|Proteomes:UP000253071};
RA   Kobmoo N., Wichadakul D., Arnamnart N., Rodriguez De La Vega R.C.,
RA   Luangsa-Ard J.-J., Giraud T.;
RT   "A genome scan of diversifying selection in the zombie-ant fungus
RT   Ophiocordyceps unilateralis complex supports a role of enterotoxins in
RT   coevolution and host-specificity.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDA94032.1}.
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DR   EMBL; PDHQ01000018; RDA94032.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A369HFM2; -.
DR   STRING; 2039874.A0A369HFM2; -.
DR   Proteomes; UP000253071; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024732; NAGLU_C.
DR   InterPro; IPR024240; NAGLU_N.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   Pfam; PF05089; NAGLU; 1.
DR   Pfam; PF12972; NAGLU_C; 1.
DR   Pfam; PF12971; NAGLU_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253071};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..785
FT                   /note="Alpha-N-acetylglucosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016836007"
FT   DOMAIN          31..123
FT                   /note="Alpha-N-acetylglucosaminidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12971"
FT   DOMAIN          138..485
FT                   /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF05089"
FT   DOMAIN          495..775
FT                   /note="Alpha-N-acetylglucosaminidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12972"
FT   REGION          631..654
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        640..654
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         785
FT                   /evidence="ECO:0000313|EMBL:RDA94032.1"
SQ   SEQUENCE   785 AA;  87278 MW;  A54F4DC6166EC986 CRC64;
     MIINFLFFLL LFVTASATTA AAAAAATATE GIAALADRIL GPGRGLSFDF ALSTEPELWS
     RWHQAGNDSY VVAVVEDGRI RIEGTTLSAL ARGLRHYATD TLHLDLYWFI GPGRQHLPPG
     PLPPPKQTLR GSSLVPWRYN LNTVTFSYSF VWYDWDEWEK LLDWSAWRGI NVQLAWVGYE
     MIYLQSFRAM GLSDDEIIPF FTGPAFQSWN RLGNVRSSWG GLGDLPLGWI QGQDTLQRRI
     VRRMVELGIT PVLPAFPGFV PDALLRVRPN STNSVTRVSW TDVPEAVGGI LFLSPLDPVY
     AELQQQFVRF QMEAYGNVSN IYALDQFNEL KPPVSGHTEE TLRAISRATD AALSAANPAA
     VWLMQGWLFF NDQSFWSPSR VDAYLGGVAD DKALVVLDLF AESEPQWNRT RSFAGRPWVW
     CMLHTFGSNM NLYGRASAVV SGLAVAQSSS SSSSSATMLL GLGLSPEGYG ANEVIYDLVL
     DQAWSATSTS QLPDWFSSWA ELRYAGVVVV PRPLIRAWQL LGAHVYDCKD EAIPSAGVGV
     YQLSPRLQGL VGRTRHFPSP TALHYDARLL RRVWRLMLAA AAEKAALWTQ PAFQLDLVDV
     TRQILSNAFT DRYEALIAAF RAAMTPPAAP TLAPLPFRRS RSDSDSDSDK SGEVAERGAD
     LLRLLDSLDL VLSAEPAYRL SKWLGDARRS AAQVVDADDL FAFNARSQIT VWLAEKHELN
     DYAARAWAGL TRSYYRPRWE VFVDGLVQAC SVGSINESAI VARIGDFERQ WQYRGFDGEA
     RPRPR
//