ID A0A369IFA3_9BACT Unreviewed; 398 AA.
AC A0A369IFA3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Methyltransferase domain-containing protein {ECO:0000313|EMBL:RDB06925.1};
GN ORFNames=DVG78_06510 {ECO:0000313|EMBL:RDB06925.1};
OS Runella aurantiaca.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae; Runella.
OX NCBI_TaxID=2282308 {ECO:0000313|EMBL:RDB06925.1, ECO:0000313|Proteomes:UP000253141};
RN [1] {ECO:0000313|EMBL:RDB06925.1, ECO:0000313|Proteomes:UP000253141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YX9 {ECO:0000313|EMBL:RDB06925.1,
RC ECO:0000313|Proteomes:UP000253141};
RA Yang X.;
RT "Genome analysis of Runella aurantiaca.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDB06925.1}.
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DR EMBL; QPIW01000003; RDB06925.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369IFA3; -.
DR OrthoDB; 9810297at2; -.
DR Proteomes; UP000253141; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 138..397
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 349
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 252
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 296
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 398 AA; 45295 MW; E8BF67558BD1C67D CRC64;
MKYHRVLVEA IVFSLTEIFE KGRQADKVIE QVLKSNRKWG ARDRGFIAEN TYEIVRWWRM
LDFVTAHLGK PAYLDFFAAW QLLKGNELPP WTEFAYIKPN AIRQAYEEAK KSRKIRESIP
DWLDEIGAAE LGTAWEDELH ALNQTAPVVL RANTLKTTAA ALKEALASKE IFTETLPGLP
DALKLREKKN VFQTDYFQNG QFEVQDAGSQ CIAPMLDVHP GMRVIDACAG AGGKTLHLAA
LMHNQGRLIA MDVEGWKLEE LRRRARRNGV SNVETRVIEP KTIKRLRDTA DRVLLDVPCS
GLGVLRRNPD SKWKMKPDFL TQIRQTQYEI LTNYSQMVKP GGKLVYATCS ILPSESEEQV
KRFLAEQGAK WQLLEEARTS PARDGFDGFY MACLTKPL
//
