ID A0A369J6W4_HYPMA Unreviewed; 401 AA.
AC A0A369J6W4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=COBW domain-containing protein 1 {ECO:0000313|EMBL:RDB14596.1};
GN Name=CBWD1 {ECO:0000313|EMBL:RDB14596.1};
GN ORFNames=Hypma_016246 {ECO:0000313|EMBL:RDB14596.1};
OS Hypsizygus marmoreus (White beech mushroom) (Agaricus marmoreus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae; Hypsizygus.
OX NCBI_TaxID=39966 {ECO:0000313|EMBL:RDB14596.1, ECO:0000313|Proteomes:UP000076154};
RN [1] {ECO:0000313|EMBL:RDB14596.1, ECO:0000313|Proteomes:UP000076154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=51987-8 {ECO:0000313|EMBL:RDB14596.1,
RC ECO:0000313|Proteomes:UP000076154};
RA Choi I.-G., Min B., Kim J.-G., Kim S., Oh Y.-L., Kong W.-S., Park H.,
RA Jeong J., Song E.-S.;
RT "Whole genome sequencing of Hypsizygus marmoreus.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDB14596.1}.
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DR EMBL; LUEZ02000096; RDB14596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369J6W4; -.
DR STRING; 39966.A0A369J6W4; -.
DR InParanoid; A0A369J6W4; -.
DR Proteomes; UP000076154; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF31; COBW DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000076154}.
FT DOMAIN 26..222
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT DOMAIN 302..384
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07683"
SQ SEQUENCE 401 AA; 43863 MW; 688A64278160C338 CRC64;
MEDDEDIPAL IEHTPASPRR TSARVPLTII CGFLGAGKST LLKRILTERH GYRIAVIMNE
FGDTADIESK TVNVSSPDDP TAEQSEEILE LANGCLCCSI KDSGVAAIEK LMQRKGAFDH
ILLETTGLAD PGPIASMFWQ NEEFATGLGR DISLDGVICV VDAVFGKQQM EEDHSEDGIG
ESLRQIAGSD VIILNKVDLV DAEKLEDTED LIHGINPAAP IHRTTRGNVD LSLIMGISAF
TSPPQLQPAH LGHHHAHAHD HDHCTDADHT HTHTPDPTHY ELRGISSLQV TCPILDQTRF
DRLDEWIRTV LWENRIPESG SGTLQVLRCK GLVTRDSGEQ YVLQGVRSIY DLAKLEGRED
ISVPQLGKIV LIGKGLDENK SLEQFCLWTC ASPDIAGGTA K
//
