ID   A0A369JF74_HYPMA        Unreviewed;       532 AA.
AC   A0A369JF74;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=DNA repair protein complementing XP-G cells {ECO:0000313|EMBL:RDB18353.1};
GN   Name=Ercc5_1 {ECO:0000313|EMBL:RDB18353.1};
GN   ORFNames=Hypma_000598 {ECO:0000313|EMBL:RDB18353.1};
OS   Hypsizygus marmoreus (White beech mushroom) (Agaricus marmoreus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae; Hypsizygus.
OX   NCBI_TaxID=39966 {ECO:0000313|EMBL:RDB18353.1, ECO:0000313|Proteomes:UP000076154};
RN   [1] {ECO:0000313|EMBL:RDB18353.1, ECO:0000313|Proteomes:UP000076154}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=51987-8 {ECO:0000313|EMBL:RDB18353.1,
RC   ECO:0000313|Proteomes:UP000076154};
RA   Choi I.-G., Min B., Kim J.-G., Kim S., Oh Y.-L., Kong W.-S., Park H.,
RA   Jeong J., Song E.-S.;
RT   "Whole genome sequencing of Hypsizygus marmoreus.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDB18353.1}.
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DR   EMBL; LUEZ02000106; RDB18353.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A369JF74; -.
DR   STRING; 39966.A0A369JF74; -.
DR   InParanoid; A0A369JF74; -.
DR   OrthoDB; 1605053at2759; -.
DR   Proteomes; UP000076154; Unassembled WGS sequence.
DR   GO; GO:0004520; F:DNA endonuclease activity; IEA:UniProt.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR   CDD; cd09870; PIN_YEN1; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR11081:SF71; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076154}.
FT   DOMAIN          124..195
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
SQ   SEQUENCE   532 AA;  58249 MW;  F33C2BB8950D477E CRC64;
     MGIPALWKVL RPAAQSRTLT QITVSEGFKT QRNEVGTISL GLDASLLLNR AQWAAYHQRN
     QGISMQAGEN LPLQILFWQV CRLLALPIST IFVFDGPGRP SIKRGETVKT APHALMRPFR
     ELIRHAGFHS YIAPGEAEAE LAKLNLIGEI DAVVTDDIDT FLFGATHILR TSNIVQDGDY
     VSIYTSTAIY DHPSIQLTRA HFLLIAVLSG GDYSNGIPGC GIATAHRLST NTMLADELFA
     ATVNLTHTEL LVFLQGWRTA LKRQLAEDPD RFLGRQLKAV ANAIPARFPD IDVLYNYVHP
     VTSWSADGDG PDISGWRNRE LDLPVLAFWC EKYFSWGSNV CIRSLLKPFN LDDALAEHAS
     GHVAGTHNMH SNILAIRRCS LGPGPPSKSP NTWGYNITVE PHTLILTTLS LLTADVRELE
     LSQPPKTFSM WLPAAILKHT LPGMVTRFHA TGKGEPNEYI VSPLLSVSPV PHLNESVEEA
     LGHGSGTASD PIIVDDDECP GLFNGDNVMQ SSVAAGPSYR ARLLLARLDE LV
//