ID A0A369JHK2_HYPMA Unreviewed; 553 AA.
AC A0A369JHK2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 {ECO:0000313|EMBL:RDB19193.1};
GN ORFNames=Hypma_013647 {ECO:0000313|EMBL:RDB19193.1};
OS Hypsizygus marmoreus (White beech mushroom) (Agaricus marmoreus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae; Hypsizygus.
OX NCBI_TaxID=39966 {ECO:0000313|EMBL:RDB19193.1, ECO:0000313|Proteomes:UP000076154};
RN [1] {ECO:0000313|EMBL:RDB19193.1, ECO:0000313|Proteomes:UP000076154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=51987-8 {ECO:0000313|EMBL:RDB19193.1,
RC ECO:0000313|Proteomes:UP000076154};
RA Choi I.-G., Min B., Kim J.-G., Kim S., Oh Y.-L., Kong W.-S., Park H.,
RA Jeong J., Song E.-S.;
RT "Whole genome sequencing of Hypsizygus marmoreus.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDB19193.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LUEZ02000080; RDB19193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369JHK2; -.
DR STRING; 39966.A0A369JHK2; -.
DR InParanoid; A0A369JHK2; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000076154; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RDB19193.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076154};
KW Transferase {ECO:0000313|EMBL:RDB19193.1}.
FT DOMAIN 17..310
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 343..550
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 553 AA; 60240 MW; 8881053DD77A4181 CRC64;
MSKSPPEISV LTIAGSDSSG GAGIQADLKA IAAHGCYGTS AITALTSQNT IGVQGVHPTP
PEFVAKQIHS ILDDIETRAI KTGMLFDADT VRAVVDALKE HYAWSTIPPL VCDPVCVSTS
GHSLLDLQAI QVLIDDLFPL ATLITPNRPE AELLLSHRQL PGKIVNIEDM IGAAQNLLEF
GSQAVLLKGG HVIASIQDIH QIIRTRNDVE IIPHNLLAEN MEILQVDEVE DVAAECVVDV
LCETGNIALL VRPRIDSMST HGTGCTLSAA IASQLALGAE LKEAVTKAVA YTHLGIQTAQ
VIGHGHGPLN HFHSLMHYSI PRQTRTNRHP FTRLLIQGNA REWKQYVEHD FVKLLGKGTL
PQKAFVHFIV QDYHYLKYYA RAYGLLAAKS TTFEAIGSAT QTIINIIHEI GTHKSFCNSF
GITNDVLEGT PEAPATTAYG AYVLDVGLQG DSTKLLMALL ACLLGYGEVG LWLKKQSSLP
NSWVILENNP YRQWMDDYAG ENYQLAVKTG LELIEGRAIA DPPSPLRFKE WKQVWDRCTI
LEIGFWDAAM AAA
//
