ID A0A369RNK3_9METZ Unreviewed; 725 AA.
AC A0A369RNK3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative serine/threonine-protein kinase pats1 {ECO:0000313|EMBL:RDD36120.1};
GN ORFNames=TrispH2_011881 {ECO:0000313|EMBL:RDD36120.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD36120.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD36120.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD36120.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD36120.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD36120.1}.
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DR EMBL; NOWV01000543; RDD36120.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369RNK3; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0070513; F:death domain binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0002020; F:protease binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR032171; COR.
DR InterPro; IPR037939; CRADD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR15034; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR PANTHER; PTHR15034:SF7; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF16095; COR; 1.
DR SMART; SM00114; CARD; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50209; CARD; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RDD36120.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transferase {ECO:0000313|EMBL:RDD36120.1}.
FT DOMAIN 620..711
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
SQ SEQUENCE 725 AA; 82546 MW; 3525E20591361992 CRC64;
MIIGPENVGK TTLLKVLIKQ SLLANEAPTQ VASGNHPLIE LITFDTGDMV KNGLGTLADS
KVGLAVLQSP SLQVTRQTLS NMKSQRTNVF DESLRSKYKK LRPKLSKIQE ANTDSNECNK
SQQSKIDNLH AVLCDFGDQA EYHVTHQPFM SCNSIYVLVF NIAEEINDAI QQRNNSKSDI
TYYARMHEWL SSVHGCKGLS DGLEGNVRNE ITIDGKNYEL PIVIVIGSHA DKIVANNEEE
KNRKIQAAYN KISPMNGDGN DNSKATQDLR DEIRKRLCQT FTKIAEKLPF ITDPIPVRWY
EIIQILRGER EDKTIKKLLT KTQVKDLIDK HHLSKQGEKL DSLLSYLHNI GQIVYCDKDE
ILSNWVVSDI DWLIEVFCSL IRISFFKSSH ADDWSDYEKI QNTGKISEEY IGHVWSKFNL
DDEERKYVLS LMTHYDILCE ISQCLQKRKW NNGRVKLYQN CASFRISPGI DLIIDKLSTV
IGLQLVYRHP NLKSKEVRRK LTKTAIELNV KDVIESALRI VLTKWMPNMS HIRIKVSVKC
PRCGELVNIE DGLSDDKSFL DCLNCGQTWL SLYQLKPWLD NIPDLTVDAF SDNGDDISMS
LTEEEGASTI PKCKTSGIGM LEIHKQILRS HYVKIIEECQ SSVKPICNHL YSREILTLHL
KEIIVCQPTD YEKMEKLLDI LPECGNRAFG AFCEVLSTIN SPVMEILENA ERKNEKGTKS
KLCNM
//
