ID A0A369RP20_9METZ Unreviewed; 660 AA.
AC A0A369RP20;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Gamma-aminobutyric acid type B receptor subunit 2 {ECO:0000313|EMBL:RDD36458.1};
DE Flags: Fragment;
GN ORFNames=TrispH2_011239 {ECO:0000313|EMBL:RDD36458.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD36458.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD36458.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD36458.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD36458.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD36458.1}.
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DR EMBL; NOWV01000379; RDD36458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369RP20; -.
DR STRING; 287889.A0A369RP20; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR CDD; cd15047; 7tmC_GABA-B-like; 1.
DR CDD; cd06366; PBP1_GABAb_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:RDD36458.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 386..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 560..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 379..608
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDD36458.1"
SQ SEQUENCE 660 AA; 74606 MW; 66C5441196ECF76F CRC64;
ASSSHALSYF LNTTRWKHKT QILISGGYSE VIASLAMVIP SFNLLQVSFA SVSSDLSDSE
KYHNFFRTCP DITHLTRPIL PVLAHYNWTS VAILHTVSVT FNRGVEILRH DLGKAGIKVL
ADEEFTYLSN LKRELKSILD SKAHIIIALI HEADAVKAFC QAFHLGLYGR EYVWFVTSWI
TENFWTNSIN DASINCTSEQ IKEAAQNYLI VDFVEIEYNN ITAVSGMTPY QFQQRYIDLA
EKKQIEKNQY VGFAYDAIWA IGLCLDNVIR ELAAENKSLD DFRYSDSFVG RTILKEMRKV
KFQGISGFKI LNNSDQEPPG VNLFRQLQGN RIVNVGLIDK NDRIDFQATE LVPIRWTGGR
PPVSGYIIEE VHAGIPFKIR ISSPNLNYLI LTGCILLYAS VIIMGIDDNT SYLNTYCKII
PWLNSIGFSL AAGSLFAKTY RAYKVLTTRF RITSPLKDSH LLAIVLILMA IEAILLTFWT
AIDPLKAEKM AAPPISDPNR YKYKIVHTYW VCTCNYGVYW LIATLILNGI VLLFGAFLAY
ESRKIKLSEL NDSKQIALCI YNITILCIII IPISFVIPNS HGEVYAAIGC LILYCTTMSL
FTFFFPKMKG NAKPSSIRFR MNENASSRMA SEKYESAMGN SELMLSCRYK EGNGKRQTAV
//
