ID A0A369RQU7_9METZ Unreviewed; 830 AA.
AC A0A369RQU7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative serine/threonine-protein kinase pats1 {ECO:0000313|EMBL:RDD37085.1};
GN ORFNames=TrispH2_011390 {ECO:0000313|EMBL:RDD37085.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD37085.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD37085.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD37085.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD37085.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD37085.1}.
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DR EMBL; NOWV01000275; RDD37085.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369RQU7; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070513; F:death domain binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0002020; F:protease binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR032171; COR.
DR InterPro; IPR037939; CRADD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR15034; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR PANTHER; PTHR15034:SF7; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF16095; COR; 1.
DR SMART; SM00114; CARD; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50209; CARD; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RDD37085.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transferase {ECO:0000313|EMBL:RDD37085.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 807..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 691..782
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
SQ SEQUENCE 830 AA; 95145 MW; 6E53F69F9FD24E0A CRC64;
MIIGPENVGK TTLLKVLIKQ SLLANEAPTQ VASGNHPLIE LITFDTGDMV KTGLGTLADS
KVGLAVLQSP FLQVTRQTLS DMKSQRTNVF DKSLRSKYSK LRPKLSKIQE ANTDSNESKK
SQQSKIDNLH AVLCDFGDQA EYHVTHQPFM SCDSIYVLVF NIAEEINDAI QQRNNSKSDI
TYFARMHEWL SSVRGCKGLR DGLGSNARNE ITIDGKYYEL PIVIVIGSHA DKIVANNEEE
KNRKIQAAYN NISREFGSKA FSKHLYLSHL AMNGDGNDNS EATQRLRDET RKQLCQIFTK
IAEKLPFITD PIPVRWYEII QILRGEREDK TIKKLLTKTQ VKDLIDKHHL SKQGEKLDSL
LSYLHNIGQI VYCDKDEILS NWVVSDIDWL IEVFCSLIRI SFFKSSHADD WSEYEKIQNT
GKISEEYIRQ VWSKFNLDDE ERKYVLSLMT HYDILCEASE LQGKDRIYLI PCLLKTQPKS
DALYPSNSTT SKYIYLGFDE KELPYISYNI FYCLISQCLQ KRGWNNGRVK LYQNCASFRI
SPGINLIIDK LSTVIGLQLV YRHPNLQSKE VRRRLTKTAV ELHVKDAIES ALRIVLTKWM
PNMSHIRIKV SVKCPYCGEL VNIEDGLSDD KSFLDCLNCE RTWHSSYHLK PWLDNITVDA
SSDNGEDTPM SLTEEERAST ISKCKNSGIG MLEIHKQILR SHRVKIIDGF KSSVKPICNH
LYSREILTPY LKEIILCQPN DYEKMDKLLD ILPERGIRAY DVFREVLSTI SSQMIKILEN
AEREYENEPK GKGKETKSYV DIFTVDIFSL PHLCIIISAL LVLNYMIHLA
//
