ID A0A369RVI5_9METZ Unreviewed; 354 AA.
AC A0A369RVI5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000313|EMBL:RDD38459.1};
GN ORFNames=TrispH2_009941 {ECO:0000313|EMBL:RDD38459.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD38459.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD38459.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD38459.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD38459.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SIMILARITY: Belongs to the ADP-ribosyl cyclase family.
CC {ECO:0000256|ARBA:ARBA00005406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD38459.1}.
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DR EMBL; NOWV01000176; RDD38459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369RVI5; -.
DR STRING; 287889.A0A369RVI5; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0061809; F:NAD+ nucleotidase, cyclic ADP-ribose generating; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd04759; Rib_hydrolase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003193; ADP-ribosyl_cyclase.
DR PANTHER; PTHR10912; ADP-RIBOSYL CYCLASE; 1.
DR PANTHER; PTHR10912:SF7; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR Pfam; PF02267; Rib_hydrolayse; 1.
DR SUPFAM; SSF52309; N-(deoxy)ribosyltransferase-like; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:RDD38459.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 306..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 354 AA; 39145 MW; 032BD8A69BEA5830 CRC64;
MSTKEQFSNL ASSAYFITFS LGLALRCQYL TTSVSGTTHN IKEIFIGRCY GYIALQNFTL
RPGVTCPSLW QEFSRVFVNR EPCEVDPTQY SRFLIESSSP VPPNKALFWS GVYDFVSSYA
QAVDDVLVIS QTFTGFLLDK LTWCGRFKST PQSEGINYLY CNDSQGCSHR NMLSFWALAS
REFAKSASGL VRVLLTSDNK TPAFNNQSIF GSIELPNLSP QKVSKVEIMV MHGLNSKPNQ
IDRCGIGSIK ELQNILTSHN FTWSCQDNPK SVLHHLCTKN PNNFHCRLAI DNSTTTNPSK
PNQSGLIIGI IIEGVVIALL VAVLLGIILR GKPGNFCSSK NGGPGSSRLM DNHE
//
