ID A0A369RXJ4_9METZ Unreviewed; 1357 AA.
AC A0A369RXJ4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=TrispH2_008461 {ECO:0000313|EMBL:RDD39406.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD39406.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD39406.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD39406.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD39406.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD39406.1}.
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DR EMBL; NOWV01000136; RDD39406.1; -; Genomic_DNA.
DR STRING; 287889.A0A369RXJ4; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843}.
FT DOMAIN 164..324
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1035..1196
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 914..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1257..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1316..1357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..938
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1357 AA; 153521 MW; ABCB4514C25A1DA0 CRC64;
MLKFKRRCTN MLQSFCGECD CSISTARYYP QTCWYQRPPN SLEGKEKRKN CATHINIISL
FAEGEANQYY PILSLLKSQI QLGFGRKAMN SAEYFKLPLK MEDLLHVSEI NSYVVEEVAT
TREIQCNIGS ANSNLRKHGA DQILNVFNLY YSVLTKHNEL DVMIKQDVWT TLLSVMKEYA
SDLTVMLEKN DINDKKKELK ILKMLSYVLV NLIEIFENSE SKSLPDLVTP RKSRKGTKKK
TTTLSWSWKN ERDAALNVIM QLLQTEISRL WDPPVVEEEY VTLISNCCYT ILEKQESAKV
NSTKDIIFHI IGILIKKYNH SLGASVKVVQ LIQHFEHLAT VMADAVAFYV NEYQANTVAS
DIIREIARIS PQELSRDSSS TRGYAVFLAE LAEKIPFVIS ANISLLISHL DGESYVMRNA
VLSTMGAIVV SLLRKDDLDE SAKKSRDHFL DRLEAHVHDV NAFVRSKVIQ ICTYVIGEKA
VPIARQPGLV ELILDRLHDK SSNVRRNAVK FLASYMARNP YGADFDVEKL ALTLENTNST
IKQLESTLDQ EKPVVKVEDQ DHDSQNHLSS EETMNEIEQK ILQHKLVARY LQDSIGFVKQ
VQNAIPIISG LLGSKTPSDV LEAVDFFVTA RSFGFNVSQN GIRKMLPLVW SREQAVKEGV
IEAYKKLYLE NTVGQNRKKD HKAIVQGLLS LVKGSTIGEL TSVEELVREF MRKGLILKET
IRLLWGYFIM AVNDVTQEDS HYALVILGMI AEEEKSFLAN NISALVDTGL GLRGEDNLVL
AKDTCHVLQK LYRRKKEIKI ARLPEDHMIF ERITTILCKG ITNLKCKFWV PFSEEAVKLV
YNLALSPEEV CKRIMQSIVK QLMPDINEGS TEDGHNEISP RLLSRFISYT GDVALCQLVH
LDVTISKELK ERRLAEDKAE ENNRTISGNK KKINSSSDED DLGLGGCVGA AADDAEMELI
RQLCDSNVVT GNGMLAVCAN FIVAVCGNSK KFNERGLQNA AAVALAKCML VSSKFCEQHL
QLLFTIVEKS QFPSVRANLA VALHDLTVRF PNLIEPWTGH LYSQLKDSSL EVKRNSIKVL
THLILNDMIK VKGQISEMAV CLEDSNKEIS NLAKLFFSEL SKKGNAVYNI LPDIISRLSD
VEVGVNEACF RSILKYVMSF IEKDRQCENL TEKLCYRFRA AKTDDRQWRN LAYCLSLLNL
NDRAFRKLYE NFSCFQHALV DDDVDSSFNT VLNKMKRFAK PETKALAEEF QDRLNESRNK
GIENDVAAQR AASAKKTPRK SVSKRKNRKK PVNLSFEEDS DVELFDIDPD EVSVNVDSDI
ENLDPATPSR CKRSTTHKRK SRSILSAKKP STISSRA
//
