ID A0A369S6T8_9METZ Unreviewed; 211 AA.
AC A0A369S6T8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Programmed cell death protein 10-A {ECO:0000313|EMBL:RDD42164.1};
GN ORFNames=TrispH2_006460 {ECO:0000313|EMBL:RDD42164.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD42164.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD42164.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD42164.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD42164.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the PDCD10 family.
CC {ECO:0000256|ARBA:ARBA00009181}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD42164.1}.
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DR EMBL; NOWV01000060; RDD42164.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369S6T8; -.
DR STRING; 287889.A0A369S6T8; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.12.70; -; 1.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR InterPro; IPR046409; PDC10_dimerisation_sf.
DR InterPro; IPR009652; PDCD10.
DR InterPro; IPR048288; PDCD10_N.
DR PANTHER; PTHR13250:SF1; PROGRAMMED CELL DEATH PROTEIN 10; 1.
DR PANTHER; PTHR13250; TF-1 CELL APOPTOSIS RELATED PROTEIN-15; 1.
DR Pfam; PF06840; PDC10_C; 1.
DR Pfam; PF20929; PDCD10_N; 1.
PE 3: Inferred from homology;
KW Angiogenesis {ECO:0000256|ARBA:ARBA00022657};
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843}.
FT DOMAIN 10..66
FT /note="Programmed cell death protein 10 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF20929"
SQ SEQUENCE 211 AA; 23997 MW; C44D8F8FF9149DAF CRC64;
MATSASKEQK VVASLALHGM VLPTIDELQQ GQNTHGAKIL RDAFVNIESQ IPGITHQFLN
AIIESDNSKT DLNFEQSMLR YAVTPCKEYQ LDRPEKEFVR LSSRSTALKS ILSRIPDDIG
DRSKFLNTIK SIASAIKEML DALNDVCKKH KDFKKLLEVQ KKEFIQQSKN FSDTLKRYFK
EENADAVFES ANRLINYTNA ILRNIRMISA K
//
