ID A0A369S805_9METZ Unreviewed; 1970 AA.
AC A0A369S805;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Fibrillin-1 {ECO:0000313|EMBL:RDD42652.1};
GN ORFNames=TrispH2_004981 {ECO:0000313|EMBL:RDD42652.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD42652.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD42652.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD42652.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD42652.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD42652.1}.
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DR EMBL; NOWV01000051; RDD42652.1; -; Genomic_DNA.
DR STRING; 287889.A0A369S805; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 26.
DR CDD; cd00104; KAZAL_FS; 2.
DR Gene3D; 3.30.60.30; -; 3.
DR Gene3D; 2.10.25.10; Laminin; 38.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR003645; Fol_N.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF198; RE68558P; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF12947; EGF_3; 16.
DR Pfam; PF07645; EGF_CA; 21.
DR SMART; SM00041; CT; 1.
DR SMART; SM00181; EGF; 38.
DR SMART; SM00179; EGF_CA; 36.
DR SMART; SM00274; FOLN; 3.
DR SMART; SM00280; KAZAL; 3.
DR SMART; SM00286; PTI; 11.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 11.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 3.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 34.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 32.
DR PROSITE; PS50026; EGF_3; 38.
DR PROSITE; PS01187; EGF_CA; 10.
DR PROSITE; PS51465; KAZAL_2; 3.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 23..65
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 66..106
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 107..149
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 150..189
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 190..230
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 240..282
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 283..323
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 324..364
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 365..406
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 407..447
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 448..487
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 488..528
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 529..568
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 569..609
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 610..653
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 654..694
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 695..732
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 733..774
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 775..815
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 816..853
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 857..897
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 898..938
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 939..980
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 981..1021
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1028..1068
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1069..1108
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1116..1156
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1157..1194
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1200..1243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1244..1279
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1283..1323
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1324..1364
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1365..1407
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1408..1449
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1450..1491
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1492..1531
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1532..1572
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1573..1613
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1632..1687
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 1712..1763
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 1840..1887
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 1896..1970
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT DISULFID 722..731
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 743..760
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1212..1229
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1970 AA; 213661 MW; EB13F077590A59D9 CRC64;
MVRTIADVRK ATKLIKFASV SVNINECSDP KQNSCHKHAT CENRPGSYVC KCKSGFQGDG
KKKCEDVDEC RKKKDKCHSL ANCTNTVGSY KCKCNAGFEG DGKQCRDINE CLKKSLHQCH
KNAKCYNSKG SYNCKCKSGF TGDGRKNCTD IDECKGKHKC KNNSKCVNTL GSYSCKCNAG
FKKVKNHCND IDECAQNKTK CHKKAKCINK IGSYTCKCNR GFTGDGMKCT GFMYNPDMPD
INECLKLKKT QCNRKTSECI NTIGSYNCKC KSGFQIINKN CADINECTKK KDNCHKHANC
KNKFGSFSCK CKPGFTGNGT DCKDINECIK RAVNCSQNAT CVNTVGSYSC KCLSGYAGNG
KRCKDINECK KGSPNKCSNN AECINTAGSY ECQCKPGYTG NGYTCNVLDK CQPGLNKCDK
NAHCSQNKTK VDCKCNDGFQ GNGISCTNIN ECKKRNKCHQ NANCIDNIGS YDCTCKPGYT
GDGLTCTDID ECQLGDNRCN DKANCKNTNG SYRCTCLSGF EGNGYNCTDK DECKGKNVCG
KKAKCINNIG SFDCQCLPGF IADGEKCKDI DECKTKAHDC DDNARCKNTN GSFNCTCNKG
YKGDGKICRD IDECSDPKLY TCKNNTSCFN TIGDYSCNCT DGFKASPNGK TCKDIDECRE
MTDKCSSDAI CVNSRGSYSC TCKKGYSGDG KICEDIDECS KPNACPKNAE CRNSVGSYAC
VCKSGFKGKK CKDINECKDS KICAHLGNST CINTIGSYEC TCGNGYTQKD EKCIDVDECL
LNTDNCHAKA TCANTIGSFS CTCKEGFRGD GLQCKDINEC ELGLANCKTN AFCINTNGSY
KCACKIGFIG HCETCEDVNE CTAGISKCDK NAACQNTIGS YTCSCKEGLH GDGRICYDTN
ECFLGIDKCH KNAKCINKWG SYECKCETGY TGDGKTCVDI DECQESDNAC NFDSNCNNTI
GSYHCKCKQG YIEGIDRNCQ DIDECKIGTA DCAATADCTN TPGSYICKCK HGYSGDGKVC
NKVSPRSNPI GCKIGGSDCI STAKCVYKAG IYKCVCKKGY IGDGTQCQQI NECDLPSMNN
CSKNAKCIDN DGGYTCQCKA GFIDYSVEGK AYECNDIDEC TEKTDDCSKN ADCVNTQGSY
TCTCKTGFSG SGIQCDDIDE CTIPNACGEN SICSNEPGSF QCKCQDGYVA INGSCFKESP
SDVCPTSIAN QCHPNATCYY VMSESSYQCI CNSGFKGEGK QCQDVDECKE KPISPSAVCI
NTPGSYKCNC KPGYEGACLL CRDIDECTTG EHTCDGNATC INELGSYKCK CKPGYKGDGQ
TCTDVNECLN GTTKCSKNAD CINLPGSYNC HCQSGYTGNG INCIPIDFCS PGGGNDCGSN
ANCIILSDGS YKCECKPGFK GDGQICKDID ECTESKTPPC HKNATCTNTK GSYFCQCKPN
YRGNGTVCED INECEDFQAC KLNQTCINLD GGYKCLCKSG YTLTADKSAC VDIDECKANS
KLCPNGLCLN LPASFTCICK DGFKRVGDDC QDNNECTAGL DDCGENADCT NTAGNYTCTC
KNGYTGDGKD CTNVDECATR KYQCSSSADC VNTIGAYQCQ CRKGFRGDGK FCDRICRPGI
CKMPGSTCTV SENNLPQCTC SCRFCSEREG QVCGTDGATY KSVKDLEMRN CMYGSIVGIE
YFGKCETSCS NVICNHNAEC KQNQTFNRPV CICPRCSRNI TRRSDNKVCG SDGITYDSEC
HLKNSNCRHA RNVQIDYIGK CDNDCQVSQW STWSTCSSTC GDSQKERNRK VIKNNGKKCP
PLKQYKPCNL PACTAELCRN IQCPYQAECT TDDSGSARCT CRKCGEVAKA PVCGSDNIDY
DSECHLQAAA CNDKKNITIS YEGKCADGGI GKPLECRRLA QKNYITNTEG TCQSQKKINV
GKCEGGCKHD KHCCKVDKTK VVKVNTSCRN GSTKNISVLV IKSCICRNNE
//
