ID A0A369S8G3_9METZ Unreviewed; 1311 AA.
AC A0A369S8G3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=UPF0577 protein KIAA1324-like {ECO:0000313|EMBL:RDD43197.1};
GN ORFNames=TrispH2_004423 {ECO:0000313|EMBL:RDD43197.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD43197.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD43197.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD43197.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD43197.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the ELAPOR family.
CC {ECO:0000256|ARBA:ARBA00007627}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD43197.1}.
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DR EMBL; NOWV01000042; RDD43197.1; -; Genomic_DNA.
DR STRING; 287889.A0A369S8G3; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR039181; EIG121-like.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR InterPro; IPR044865; MRH_dom.
DR InterPro; IPR013909; NIPA/Rsm1_C.
DR InterPro; IPR012935; Znf_C3HC-like.
DR PANTHER; PTHR22727:SF15; MRH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22727; PROTEIN CBG13728; 1.
DR Pfam; PF08600; Rsm1; 1.
DR Pfam; PF07967; zf-C3HC; 1.
DR SMART; SM01411; Ephrin_rec_like; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR PROSITE; PS51914; MRH; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1209..1230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 952..1148
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
SQ SEQUENCE 1311 AA; 146518 MW; 79A2110034325E30 CRC64;
MAEISLVPRK FLSLLDSFIF DKPACPENEC KQDKVAEDYF ERVETYSAYT WLAKPPALSP
LQCARYGWKN VDIDRLKCVT CSATLTVSLP LPSTRSQPYE EAVRTFTDAL ISRHNPLCPW
KDAPVREELI RLPNTYAKCV PILRQRLKSY SSAPHLLPRL ELNSTLNTLL SCKEAVETLK
DILDCQVILT DVDEEAQMVA CILAFCGWVL KPSDKLKSSL LICSICRRRA GIWNYIMAIS
DSSTDSLELS SESIEEQSSS SPSKRRKIEK KKFNPIEEHR YWCPYFIVDD NNAESREDVE
RSLGNVHQDN NNDTAGLKSM LSYLFPKRHS RTTDPNLNSV QPEQVLQTDD FDYQYTSCDG
AGNRWRVAIP KEGKNCSSGA VPLPVLGRKC DFHCNPGQYM DINGDQSCHG CPGGTYSNGN
TMTFQKWDQL LPGWESSGYA NHYDTGDSNS IRNCTKANWV TGGGYIISAA SRSCYSMLTY
SVDLIEAGSV EFEYKIEDDR VTLVVETKSS EKCLKSKNTE RAYITKTGNV WKKKTLPLPA
GRSVIIWDTG IVYYVTEKTK VPPVYIRYVK ITGVPYTYEC MSCPAGTYSG EGASYCLLCP
DNTYSEGNTT KCSSCDSKSE YAERGATKCA KRPACKEEDY FETFTVCDGN KQTQKMYKWN
EPKLCREDLK GAVTLPASGE KIKCQLCNPG TFLKGNHCEI CPANQYGDGE SGCSPCPPST
SAIRGHYYQW WSALPSNVTL SCVSPYTQGC ATMDGWRLRN TYIDSGVGHD GDTYLELVLK
VKGFAEPEVN SGLKQGEFGK LTFVFETRCQ GSCKLSLYMA GKHHFNGELS SWHGAQSKQT
YSYIVTDPHV NRFIWEFSRD NNADNSNKDD RVIIYSINVT NTIDGGAYRC NACPVGTKDS
RCIPCPKGQY INNATKNCVK CPKNTYLKNN QLSGAAACEK CGPGTFSEEG SVRCSYSCQY
KSDNGDQYDF TKLSSPQLVE TGPSFTAEGT NYHHVFNVSI CGKTSTCRTN FSAAIRGSHR
DRETYLDASI CRSTIIHWKD NKKIAAQPIS LGNYLAGISS KNILGNVSFR GFEEKADKSS
GVKDIHYFFK NNAPTRACPR GRSVVIALRC DATAGSTGII KLPTKCPSGT CDGCNFNFLW
RTKYACPICQ KKDYTIIHSK CQNSTKTTHY VWKHQPKICR DGVSLPPKKE QKCTIMERTI
GAAVQDFKII IILVAVAAVV LILALVGLYL RNRKLSHRYV KLQQNLNTKD SEMPAPETCV
IDDDDDEEEI IFNNGRGKKN QQTFKDNQGH HDDAFDTVLL EKGNKDTNKM I
//
