ID A0A369SE61_9METZ Unreviewed; 774 AA.
AC A0A369SE61;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Gamma-aminobutyric acid type B receptor subunit 2 {ECO:0000313|EMBL:RDD44293.1};
GN ORFNames=TrispH2_003275 {ECO:0000313|EMBL:RDD44293.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD44293.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD44293.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD44293.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD44293.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD44293.1}.
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DR EMBL; NOWV01000027; RDD44293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SE61; -.
DR STRING; 287889.A0A369SE61; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR CDD; cd15047; 7tmC_GABA-B-like; 1.
DR CDD; cd06366; PBP1_GABAb_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:RDD44293.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 588..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 478..732
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 774 AA; 87458 MW; 921EB1510305556A CRC64;
MYHSRSLHHY FMIIKAISVI LAISGYRIVA SAEAENKQDS TLNIGGFYAF NNSLGKHLYG
PEISTVAQIA VEEINNSTSI LPNHKLKLFV ENTHGSVNYA QRAFFNYVYY KPTKIMLLGA
DFSTVTEPLA TTSSLWNLIQ VSFASTSPVL SNRQRFPYFY RTVQSDIDYN DPRIALLRYF
RWTTVGILYQ LENIFSEAMS SLRTSLTAAN IKINGYETFR EDPYDAVRAL KSRDARIIIA
NFYEKQGAHV LCEAYHQNMR GGKYVWILLG WLQGQWWNTT VIARSGNCTS KELIEVLDNH
FTTDLVYLND DNETIPSGKN VKQLVAELED RLGYPPQTHG YYPFAYDAIY AMAFAMNVTE
NQLSKNNKSL SQFHYGDITM AKMLKDNMDY VKFRGLTGPV SFKSTGDREG NTKINQIQFE
GNVGNKVLVG IYKSSSKEIV MNRQLIRWTD NSTPVAAVRR IIEPTSINLD LFIGACATAA
LGIVLAIGFL IFNLVYRNHR YIKMSSPNLN NIIILGCIIM YASVCVFGLD NRFIPEHLLV
LICSLRMWVP IIGFTLAFGT MFAKTYRIYK IFVGSRSNKK VIITDTQLVI LVGILLSIDF
ILLATWQLID PPTIQRFNIS TYQKSQDETI VSQIWLCHSK HNLYWFIALY TEKGLLLLAG
MFLAWETRGV RYAALNDSQY IAMSVYNVVI LSGVGVLVVS IMAKSINAAY ALMSALLIFG
NTVILCLVFV PKFIEFKRKD DPIHGDSRRP SMNPSAMQSI SATNMALISK TPSA
//
